The role of vitamin C in stress-related disorders

B Moritz, AE Schmitz, ALS Rodrigues, AL Dafre… - The Journal of …, 2020 - Elsevier
Stress-related disorders, such as depression and anxiety, present marked deficits in
behavioral and cognitive functions related to reward. These are highly prevalent disabling …

Antioxidant biomolecules and their potential for the treatment of difficult-to-treat depression and conventional treatment-resistant depression

ME Riveros, A Ávila, K Schruers, F Ezquer - Antioxidants, 2022 - mdpi.com
Major depression is a devastating disease affecting an increasing number of people from a
young age worldwide, a situation that is expected to be worsened by the COVID-19 …

Aging and its treatment with vitamin C: a comprehensive mechanistic review

S Mumtaz, S Ali, HM Tahir, SAR Kazmi… - Molecular biology …, 2021 - Springer
Aging and age-related disorders have become one of the prominent issue of world.
Oxidative stress due to overproduction of reactive oxygen species is the most significant …

Relationship of oxidative stress as a link between diabetes mellitus and major depressive disorder

GZ Réus, AS Carlessi, RH Silva… - Oxidative medicine …, 2019 - Wiley Online Library
Both conditions, major depressive disorder (MDD) and diabetes mellitus (DM) are chronic
and disabling diseases that affect a very significant percentage of the world's population …

A ratiometric fluorescence-scattered light strategy based on MoS2 quantum dots/CoOOH nanoflakes system for ascorbic acid detection

Z Wu, D Nan, H Yang, S Pan, H Liu, X Hu - Analytica Chimica Acta, 2019 - Elsevier
A facile ratiometric fluorescence method for ascorbic acid (AA) detection was established by
combining the fluorescence of MoS 2 quantum dots (QDs) with second-order scattering …

Anti-alzheimer activity of combinations of cocoa with vinpocetine or other nutraceuticals in rat model: modulation of wnt3/β-catenin/GSK-3β/nrf2/HO-1 and PERK …

K Abu-Elfotuh, AMA Tolba, FH Hussein, AME Hamdan… - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD) is a devastating illness with limited therapeutic interventions. The
aim of this study is to investigate the pathophysiological mechanisms underlying AD and …

Inhibition of histone acetyltransferase by naringenin and hesperetin suppresses Txnip expression and protects pancreatic β cells in diabetic mice

S Wang, H Sheng, Y Bai, Y Weng, X Fan, F Zheng, J Fu… - Phytomedicine, 2021 - Elsevier
Background The damage of pancreatic β cells is a major pathogenesis of the development
and progression of type 2 diabetes and there is still no effective therapy to protect pancreatic …

The use of bioactive compounds in hyperglycemia-and amyloid fibrils-induced toxicity in type 2 diabetes and Alzheimer's disease

AV Lupaescu, M Iavorschi, M Covasa - Pharmaceutics, 2022 - mdpi.com
It has become increasingly apparent that defective insulin signaling may increase the risk for
developing Alzheimer's disease (AD), influence neurodegeneration through promotion of …

Neurological and metabolic related pathophysiologies and treatment of comorbid diabetes with depression

S Li, D Yang, X Zhou, L Chen, L Liu… - CNS Neuroscience …, 2024 - Wiley Online Library
Background The comorbidity between diabetes mellitus and depression was revealed, and
diabetes mellitus increased the prevalence of depressive disorder, which ranked 13th in the …

Comparative effects of curcumin versus nano-curcumin on histological, immunohistochemical expression, histomorphometric, and biochemical changes to pancreatic …

MR Metawea, HMA Abdelrazek, HNG El-Hak… - … Science and Pollution …, 2023 - Springer
Diabetes mellitus is a worldwide problem characterized by hyperglycemia as well as the
damage of the microscopic structure of the beta cells of Langerhans pancreatic islets. In the …