Proteogenomics: concepts, applications and computational strategies

AI Nesvizhskii - Nature methods, 2014 - nature.com
Proteogenomics is an area of research at the interface of proteomics and genomics. In this
approach, customized protein sequence databases generated using genomic and …

Malaria: influence of Anopheles mosquito saliva on Plasmodium infection

G Arora, YM Chuang, P Sinnis, G Dimopoulos… - Trends in …, 2023 - cell.com
Malaria is caused by Plasmodium protozoa that are transmitted by anopheline mosquitoes.
Plasmodium sporozoites are released with saliva when an infected female mosquito takes a …

Proteomic analysis of Chinese hamster ovary cells

D Baycin-Hizal, DL Tabb, R Chaerkady… - Journal of proteome …, 2012 - ACS Publications
To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells,
proteomic analysis was performed on CHO cells including the cellular proteome, secretome …

Electron transfer dissociation mass spectrometry in proteomics

MS Kim, A Pandey - Proteomics, 2012 - Wiley Online Library
Mass spectrometry has rapidly evolved to become the platform of choice for proteomic
analysis. While CID remains the major fragmentation method for peptide sequencing …

Daily rhythms in antennal protein and olfactory sensitivity in the malaria mosquito Anopheles gambiae

SSC Rund, NA Bonar, MM Champion, JP Ghazi… - Scientific reports, 2013 - nature.com
We recently characterized 24-hr daily rhythmic patterns of gene expression in Anopheles
gambiae mosquitoes. These include numerous odorant binding proteins (OBPs), soluble …

Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for population replacement

A Hoermann, S Tapanelli, P Capriotti, G Del Corsano… - Elife, 2021 - elifesciences.org
Gene drives for mosquito population replacement are promising tools for malaria control.
However, there is currently no clear pathway for safely testing such tools in endemic …

Anopheline salivary protein genes and gene families: an evolutionary overview after the whole genome sequence of sixteen Anopheles species

B Arcà, F Lombardo, CJ Struchiner, JMC Ribeiro - BMC genomics, 2017 - Springer
Background Mosquito saliva is a complex cocktail whose pharmacological properties play
an essential role in blood feeding by counteracting host physiological response to tissue …

Addressing statistical biases in nucleotide-derived protein databases for proteogenomic search strategies

P Blakeley, IM Overton, SJ Hubbard - Journal of proteome …, 2012 - ACS Publications
Proteogenomics has the potential to advance genome annotation through high quality
peptide identifications derived from mass spectrometry experiments, which demonstrate a …

Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host

A Roth, SR Adapa, M Zhang, X Liao, V Saxena… - Scientific reports, 2018 - nature.com
Malaria parasites transmitted by mosquito bite are remarkably efficient in establishing
human infections. The infection process requires roughly 30 minutes and is highly complex …

Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes

TSK Prasad, AK Mohanty, M Kumar… - Genome …, 2017 - genome.cshlp.org
Complementing genome sequence with deep transcriptome and proteome data could
enable more accurate assembly and annotation of newly sequenced genomes. Here, we …