Proteogenomics: concepts, applications and computational strategies
AI Nesvizhskii - Nature methods, 2014 - nature.com
Proteogenomics is an area of research at the interface of proteomics and genomics. In this
approach, customized protein sequence databases generated using genomic and …
approach, customized protein sequence databases generated using genomic and …
Malaria: influence of Anopheles mosquito saliva on Plasmodium infection
Malaria is caused by Plasmodium protozoa that are transmitted by anopheline mosquitoes.
Plasmodium sporozoites are released with saliva when an infected female mosquito takes a …
Plasmodium sporozoites are released with saliva when an infected female mosquito takes a …
Proteomic analysis of Chinese hamster ovary cells
D Baycin-Hizal, DL Tabb, R Chaerkady… - Journal of proteome …, 2012 - ACS Publications
To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells,
proteomic analysis was performed on CHO cells including the cellular proteome, secretome …
proteomic analysis was performed on CHO cells including the cellular proteome, secretome …
Electron transfer dissociation mass spectrometry in proteomics
Mass spectrometry has rapidly evolved to become the platform of choice for proteomic
analysis. While CID remains the major fragmentation method for peptide sequencing …
analysis. While CID remains the major fragmentation method for peptide sequencing …
Daily rhythms in antennal protein and olfactory sensitivity in the malaria mosquito Anopheles gambiae
SSC Rund, NA Bonar, MM Champion, JP Ghazi… - Scientific reports, 2013 - nature.com
We recently characterized 24-hr daily rhythmic patterns of gene expression in Anopheles
gambiae mosquitoes. These include numerous odorant binding proteins (OBPs), soluble …
gambiae mosquitoes. These include numerous odorant binding proteins (OBPs), soluble …
Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for population replacement
A Hoermann, S Tapanelli, P Capriotti, G Del Corsano… - Elife, 2021 - elifesciences.org
Gene drives for mosquito population replacement are promising tools for malaria control.
However, there is currently no clear pathway for safely testing such tools in endemic …
However, there is currently no clear pathway for safely testing such tools in endemic …
Anopheline salivary protein genes and gene families: an evolutionary overview after the whole genome sequence of sixteen Anopheles species
Background Mosquito saliva is a complex cocktail whose pharmacological properties play
an essential role in blood feeding by counteracting host physiological response to tissue …
an essential role in blood feeding by counteracting host physiological response to tissue …
Addressing statistical biases in nucleotide-derived protein databases for proteogenomic search strategies
P Blakeley, IM Overton, SJ Hubbard - Journal of proteome …, 2012 - ACS Publications
Proteogenomics has the potential to advance genome annotation through high quality
peptide identifications derived from mass spectrometry experiments, which demonstrate a …
peptide identifications derived from mass spectrometry experiments, which demonstrate a …
Unraveling the Plasmodium vivax sporozoite transcriptional journey from mosquito vector to human host
Malaria parasites transmitted by mosquito bite are remarkably efficient in establishing
human infections. The infection process requires roughly 30 minutes and is highly complex …
human infections. The infection process requires roughly 30 minutes and is highly complex …
Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes
Complementing genome sequence with deep transcriptome and proteome data could
enable more accurate assembly and annotation of newly sequenced genomes. Here, we …
enable more accurate assembly and annotation of newly sequenced genomes. Here, we …