Pseudomonas aeruginosa is a major, but opportunistic, respiratory pathogen, which rarely
infects healthy individuals, mainly due to the barrier effect of the human airway epithelium …

Pseudomonas aeruginosa is an opportunistic pathogen heavily implicated in chronic
diseases. Immunocompromised patients that become infected with P. aeruginosa usually …

CD59 is an abundant immuno-regulatory receptor that protects human cells from damage
during complement activation. Here we show how the receptor binds complement proteins …

Fluorescence techniques dominate the field of live-cell microscopy, but bleaching and
motion blur from too long integration times limit dynamic investigations of small objects. High …

Bacterial adhesion, biofilm formation and host cell invasion of the ESKAPE pathogen
Pseudomonas aeruginosa require the tetravalent lectins LecA and LecB, which are …

Background Aberrant glycosylation patterns play a crucial role in the development of cancer
cells as they promote tumor growth and aggressiveness. Lectins recognize carbohydrate …

Septin GTPases polymerize into higher-ordered structures as a part of the cytoskeleton and
are involved in interactions of the host with a wide spectrum of pathogens. Many pathogens …

Protein toxins secreted by bacteria and found in plants can be threats to human health.
However, their extreme toxicity can also be exploited in different ways, eg, to produce hybrid …

Pseudomonas aeruginosa is a significant cause of global morbidity and mortality. Although it
is often regarded as an extracellular pathogen toward human cells, numerous investigations …

Highlights•Manipulation of the host cell plasma membrane is critical for infection by
intracellular bacterial pathogens.•Plasma membrane manipulation occurs during bacterial …