“Minimally symptomatic” congenital cytomegalovirus infection: latest data and emerging concepts

A Howard, JK Nishikawa… - Current Opinion in …, 2024 - journals.lww.com
Antiviral therapy with either ganciclovir or valganciclovir has shown moderate benefit in
prevention of hearing deterioration among infants with clinically apparent CMV infection or …

Prenatal and postnatal antiviral therapies for the prevention and treatment of congenital cytomegalovirus infections

P Chandrasekaran, HS Lee, L Hui… - Current Opinion in …, 2024 - journals.lww.com
More research is needed to determine the region-specific applicability of the new European
recommendations for routine CMV screening in pregnancy. Areas of uncertainty in postnatal …

A cross-sectional survey of pediatric infectious disease physicians' approach to congenital cytomegalovirus infection

C Hoki, M White, MH Pesch, AJ Melvin… - International Journal of …, 2023 - mdpi.com
Congenital cytomegalovirus (cCMV) continues to be a major public health care issue due to
its high prevalence throughout the world. However, there is a paucity of studies evaluating …

[HTML][HTML] Valganciclovir in infants with hearing loss and clinically Inapparent congenital cytomegalovirus infection: a nonrandomized controlled trial

PK Chung, FAJ Schornagel, W Soede… - The Journal of …, 2024 - Elsevier
Objective To assess the efficacy of valganciclovir in infants with hearing loss and clinically
inapparent congenital cytomegalovirus infection (cCMV), as there is no consensus on …

Considering antiviral treatment to preserve hearing in congenital CMV

TM Lanzieri, MH Pesch, SD Grosse - Pediatrics, 2023 - publications.aap.org
Congenital cytomegalovirus (cCMV) infection is the leading nongenetic cause of
sensorineural hearing loss (SNHL) in children. 1 In the United States, cCMV occurs in an …

Ganciclovir and valganciclovir use among infants with congenital cytomegalovirus: data from a multicenter electronic health record dataset in the United States

J Leung, SD Grosse, B Yockey… - Journal of the Pediatric …, 2022 - academic.oup.com
Among 342 US infants with congenital cytomegalovirus treated with antivirals, 114 (33%)
received ganciclovir (with or without valganciclovir) and 228 (67%) received valganciclovir …

The audiological follow-up of children with symptomatic congenital cytomegalovirus infection: an experience in two Italian centers

S Palma, F Forli, C Rossi, R Filice, C D'adamo… - Children, 2023 - mdpi.com
Background: Congenital cytomegalovirus (cCMV) infection is the leading cause of non-
hereditary sensorineural hearing loss in children. While about 10% of children reportedly …

Detecting Hearing Loss Through Targeted Surveillance: Risk Registry and Surveillance Timeframe Recommendations

EJ Fitzgibbons, C Driscoll, L Traves, R Beswick - Journal of Speech …, 2024 - ASHA
Purpose: The purpose of this study was to inform the revision of a targeted surveillance risk
registry by identifying which risk factors predict postnatally identified hearing loss (PNIHL) in …

Ophthalmic Complications, Diagnosis, and Treatment of Congenital Human Cytomegalovirus Infection

M Modrzejewska, P Połubiński… - Journal of Clinical …, 2024 - mdpi.com
Background: Human cytomegalovirus (hCMV) is the most common etiological agent of
congenital infections seen in newborns. Among the most commonly observed complications …

Clinical Practice Guidelines for the Management of Congenital Cytomegalovirus Infection in Japan 2023: Executive Summary

Y Ito, I Morioka, N Takahashi, K Fujioka… - The Pediatric …, 2024 - journals.lww.com
Congenital cytomegalovirus (cCMV) infection is the most common congenital infection in
developed countries. Although a standard therapy has not yet been established, evidence …