Development and Validation of a UPLC-MS/MS Method for Therapeutic Drug Monitoring, Pharmacokinetic and Stability Studies of First-Line Antituberculosis Drugs in …

M Abouzid, K Kosicka-Noworzyń… - Molecules, 2024 - mdpi.com
Tuberculosis (TB) remains one of the leading global causes of mortality. Several methods
have been established to detect anti-TB agents in human plasma and serum. However …

A systematic review on the effect of diabetes mellitus on the pharmacokinetics of TB drugs

M Cevik, A Sturdy, AE Maraolo… - … of Tuberculosis and …, 2024 - ingentaconnect.com
OBJECTIVESThe coexistence of TB and diabetes mellitus (DM)(TB-DM) is associated with
an increased risk of treatment failure, death, delayed culture conversion, and drug …

A Systematic Review on the Effect of Diabetes Mellitus on the Pharmacokinetics of Tuberculosis Drugs

M Cevik, A Sturdy, AE Maraolo, BGJ Dekkers… - medRxiv, 2023 - medrxiv.org
While pharmacokinetics (PK) of many drugs is known to be altered in individuals with
diabetes mellitus (DM), the effects of DM on the PK of anti-tuberculosis (TB) drugs remains …

Isoniazid urine spectrophotometry for prediction of serum pharmacokinetics in adults with TB

PS Rao, K Reed, N Modi, D Handler… - IJTLD …, 2024 - ingentaconnect.com
BACKGROUNDIsoniazid (INH) is an important drug in many TB regimens, and unfavorable
treatment outcomes can be caused by suboptimal pharmacokinetics. Dose adjustment can …