The study is aimed to investigate the effect of stretch stress with different intensities on the
differentiation and apoptosis of human plate chondrocytes. In the present study, the human …

Purpose: Teeth are exposed to various forces during functional and parafunctional
movements. These processes inevitably affect the dental pulp, and the mechanism of these …

The study was aimed to investigate the role of the “extracellular matrix (ECM)-integrins-
cytoskeleton” signal pathway in mechanotransduction of centrifugal loading. MG-63 …

Biomechanical force is one of the major epigenetic factors that determine the form and
differentiation of skeletal tissues. In this study, osteoblastic cells UMR-106 were exposed to …

IL‐6 has a dual role in bone remodelling. The ERK1/2 pathway partially upregulated IL‐6
secretion in osteocyte‐like MLO‐Y4 cells exposed to CCF. We have now investigated the …

Although osteocytes have long been regarded as mechanosensors for translating
mechanical signals into biochemical signals to regulate the other bone cells, the global …

We previously reported that cyclic compressive force (CCF) induced interleukin-6 mRNA
expression in osteocyte-like MLO-Y4 cells. But little is known about how the stimuli are …

AIMS: Orthodontic forces are known to aggravate inflammation-induced destruction of the
periodontium, but the underlying mechanism has not been elucidated. The present study …

We previously revealed the involvement of extracellular regulated protein kinases 1/2
(ERK1/2) in interleukin-6 (IL-6) secretion induced by cyclic compressive force (CCF) in MLO …

OBJECTIVE: To investigate the effect of constant compressive stress induced by imitating
Tuina stimulation with various durations on the cell cycle, cellular secretion, apoptosis, and …