The synapsins: key actors of synapse function and plasticity
The synapsins are a family of neuronal phosphoproteins evolutionarily conserved in
invertebrate and vertebrate organisms. Their best-characterised function is to modulate …
invertebrate and vertebrate organisms. Their best-characterised function is to modulate …
Schizophrenia: genes and environment
M Tsuang - Biological psychiatry, 2000 - Elsevier
The historical and genetic foundations of our current understanding of schizophrenia are
reviewed, as are the present and future directions for research. Genetic epidemiological …
reviewed, as are the present and future directions for research. Genetic epidemiological …
[HTML][HTML] Neuregulin 1 and susceptibility to schizophrenia
H Stefansson, H Petursson, E Sigurdsson… - The American Journal of …, 2002 - cell.com
The cause of schizophrenia is unknown, but it has a significant genetic component.
Pharmacologic studies, studies of gene expression in man, and studies of mouse mutants …
Pharmacologic studies, studies of gene expression in man, and studies of mouse mutants …
[HTML][HTML] Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia
CM Lewis, DF Levinson, LH Wise, LE DeLisi… - The American Journal of …, 2003 - cell.com
Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to
siblings of probands. Replication has been inconsistent for reports of significant genetic …
siblings of probands. Replication has been inconsistent for reports of significant genetic …
Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the “two hit hypothesis”
Schizophrenia is a psychiatric disorder that a icts 0.5±1% of the general population. It is
clinically characterized by disturbed thought processes, delusions, hallucinations and/or …
clinically characterized by disturbed thought processes, delusions, hallucinations and/or …
[HTML][HTML] Methamphetamine-associated psychosis
Methamphetamine (METH) is a frequent drug of abuse in US populations and commonly
associated with psychosis. This may be a factor in frequent criminal justice referrals and …
associated with psychosis. This may be a factor in frequent criminal justice referrals and …
Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology
PJ Harrison, AJ Law - Biological psychiatry, 2006 - Elsevier
Neuregulin 1 (NRG1) is a leading schizophrenia susceptibility gene. The NRG1 locus on
chromosome 8p shows linkage to the disorder, and genetic association has been found …
chromosome 8p shows linkage to the disorder, and genetic association has been found …
[HTML][HTML] Association of neuregulin 1 with schizophrenia confirmed in a Scottish population
H Stefansson, J Sarginson, A Kong, P Yates… - The American Journal of …, 2003 - cell.com
Recently, we identified neuregulin 1 (NRG1) as a susceptibility gene for schizophrenia in the
Icelandic population, by a combined linkage and association approach. Here, we report the …
Icelandic population, by a combined linkage and association approach. Here, we report the …
Genes, environment and schizophrenia
BackgroundData from family, twin and adoption studies show overwhelming evidence of a
substantial genetic component in schizophrenia and although molecular genetic studies …
substantial genetic component in schizophrenia and although molecular genetic studies …
Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease
AJ Law, BK Lipska, CS Weickert… - Proceedings of the …, 2006 - National Acad Sciences
Genetic variation in neuregulin 1 (NRG1) is associated with schizophrenia. The disease-
associated SNPs are noncoding, and their functional implications remain unknown. We …
associated SNPs are noncoding, and their functional implications remain unknown. We …