Hair cells (HCs) are specialised sensory receptors residing in the neurosensory epithelia of
inner ear sense organs. The precise morphological and physiological properties of HCs …

All epistemic agents physically consist of parts that must somehow comprise an integrated
cognitive self. Biological individuals consist of subunits (organs, cells, and molecular …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

The emergence of large gene expression datasets has revealed the need for improved tools
to identify enriched gene categories and visualize enrichment patterns. While gene …

The genome of Caenorhabditis elegans encodes 284 nuclear hormone receptor, which
perform diverse functions in development and physiology. One of the best characterized of …

Targeting glycolysis has been considered therapeutically intractable owing to its essential
housekeeping role. However, the context-dependent requirement for individual glycolytic …

Metabolism is controlled to ensure organismal development and homeostasis. Several
mechanisms regulate metabolism, including allosteric control and transcriptional regulation …

The human microbiota is believed to influence health. Microbiome dysbiosis may be linked
to neurological conditions like Alzheimer's disease, amyotrophic lateral sclerosis, and …

The cell stress‐responsive transcription factor p53 influences the expression of its target
genes and subsequent cellular responses based in part on its dynamics (changes in level …

Vitamin B12 is an essential micronutrient that functions in two metabolic pathways: the
canonical propionate breakdown pathway and the methionine/S-adenosylmethionine …