A comprehensive review: Biological activity, modification and synthetic methodologies of prenylated flavonoids

S Shi, J Li, X Zhao, Q Liu, SJ Song - Phytochemistry, 2021 - Elsevier
Prenylated flavonoids, a unique class of flavonoids which combine a flavonoid skeleton and
a lipophilic prenyl side-chain, possess great potential biological activities including …

Phytochemistry and pharmacology of natural prenylated flavonoids

HW Lv, QL Wang, M Luo, MD Zhu, HM Liang… - Archives of Pharmacal …, 2023 - Springer
Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more
prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain …

Crocin molecular signaling pathways at a glance: A comprehensive review

M Boozari, H Hosseinzadeh - Phytotherapy Research, 2022 - Wiley Online Library
Crocin is a hydrophilic carotenoid that is synthesized in the flowers of the Crocus genus.
Numerous in vitro and in vivo research projects have been published about the biological …

Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

Immunomodulatory potential of flavonoids for the treatment of autoimmune diseases and tumour

L Han, Q Fu, C Deng, L Luo, T Xiang… - … Journal of Immunology, 2022 - Wiley Online Library
The immune system plays an indispensable role in maintaining human health against the
invasion of foreign materials, microorgainisms and pathogens. The autoimmune diseases …

Quercetin radiosensitizes non‐small cell lung cancer cells through the regulation of miR‐16‐5p/WEE1 axis

Q Wang, Y Chen, H Lu, H Wang, H Feng, J Xu… - IUBMB …, 2020 - Wiley Online Library
Background Quercetin, a widely distributed bioflavonoid, plays a role in combating diverse
human cancers including non‐small cell lung cancer (NSCLC). However, the role of …

Mechanisms of traditional chinese medicine/natural medicine in HR-positive breast cancer: A comprehensive literature review

Q Yu, C Xu, J Song, Y Jin, X Gao - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance With the emergence of endocrine resistance, the survival
and good prognosis of HR-positive breast cancer (HR+ BC) patients are threatened. As a …

Flos Sophorae Immaturus: Phytochemistry, bioactivities, and its potential applications

Y Gong, L Fan, L Wang, J Li - Food Reviews International, 2023 - Taylor & Francis
ABSTRACT Flos Sophorae Immaturus (FSI) is a dried flower bud derived from Sophora
japonica L. FSI contains various phytochemicals, including rutin, quercetin, kaempferol …

Targeting Wnt/β-catenin pathway by flavonoids: implication for cancer therapeutics

P Pandey, F Khan, SA Seifeldin, K Alshaghdali… - Nutrients, 2023 - mdpi.com
The Wnt pathway has been recognized for its crucial role in human development and
homeostasis, but its dysregulation has also been linked to several disorders, including …

Flavonostilbenes natural hybrids from Rhamnoneuron balansae as potential antitumors targeting ALDH1A1: molecular docking, ADMET, MM-GBSA calculations and …

T Elsaman, I Ahmad, EM Eltayib… - Journal of …, 2024 - Taylor & Francis
Several studies have linked Cancer stem cells (CSCs) to cancer resistance development to
chemotherapy and radiotherapy. ALDH1A1 is a key enzyme that regulates the gene …