miRNAs in cancer (review of literature)

B Smolarz, A Durczyński, H Romanowicz… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …

Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

The role of the tumor microenvironment and treatment strategies in colorectal cancer

Y Chen, X Zheng, C Wu - Frontiers in immunology, 2021 - frontiersin.org
Colorectal cancer (CRC) has the second highest mortality rate among all cancers
worldwide. Surgery, chemotherapy, radiotherapy, molecular targeting and other treatment …

Identification of a six‐microRNA signature as a potential diagnostic biomarker in breast cancer tissues

M Mahmoudian, E Razmara… - Journal of clinical …, 2021 - Wiley Online Library
Background Breast cancer (BC) is by far the most common malignancy among women.
Epigenetic modulators, microRNAs in particular, may set stages for BC development and its …

Colorectal cancer cell-derived extracellular vesicles transfer miR-221-3p to promote endothelial cell angiogenesis via targeting suppressor of cytokine signaling 3

M Dokhanchi, K Pakravan, S Zareian, BM Hussen… - Life Sciences, 2021 - Elsevier
Abstract Background Secreted microRNAs (miRNAs) can serve as promising diagnostic
markers for colorectal cancer (CRC). Herein, we evaluated the potential clinical significance …

Current advances in detecting genetic and epigenetic biomarkers of colorectal cancer

MS Islam, V Gopalan, AKY Lam… - Biosensors and …, 2023 - Elsevier
Colorectal carcinoma (CRC) is the third most common cancer in terms of diagnosis and the
second in terms of mortality. Recent studies have shown that various proteins, such as …

[HTML][HTML] Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm

M Roshani, D Molavizadeh, S Sadeghi, A Jafari… - Biomedicine & …, 2023 - Elsevier
Gastrointestinal (GI) carcinomas are a group of cancers affecting the GI tract and digestive
organs, such as the gastric, liver, bile ducts, pancreas, small intestine, esophagus, colon …

Epigenetic landscape of liquid biopsy in colorectal cancer

A Rodriguez-Casanova, N Costa-Fraga… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignancies and is a major cause of
cancer-related deaths worldwide. Thus, there is a clinical need to improve early detection of …

Circulating miRNA as biomarkers for colorectal cancer diagnosis and liver metastasis

FJ Nassar, ZS Msheik, MM Itani, RE Helou, R Hadla… - Diagnostics, 2021 - mdpi.com
Colorectal cancer (CRC) is the second leading cause of cancer deaths worldwide. Stage IV
CRC patients have poor prognosis with a five-year survival rate of 14%. Liver metastasis is …

[HTML][HTML] MicroRNAs as important contributors in the pathogenesis of colorectal cancer

S Ghafouri-Fard, BM Hussen, E Badrlou, A Abak… - Biomedicine & …, 2021 - Elsevier
Colorectal cancer (CRC) is the third most fatal and fourth most frequently diagnosed
neoplasm in the world. Numerous non-coding RNAs have been shown to contribute in the …