The naked mole-rat response to oxidative stress: just deal with it

KN Lewis, B Andziak, T Yang… - Antioxidants & redox …, 2013 - liebertpub.com
Significance: The oxidative stress theory of aging has been the most widely accepted theory
of aging providing insights into why we age and die for over 50 years, despite mounting …

Nrf2, a guardian of healthspan and gatekeeper of species longevity

KN Lewis, J Mele, JD Hayes… - … and comparative biology, 2010 - academic.oup.com
Although aging is a ubiquitous process that prevails in all organisms, the mechanisms
governing both the rate of decline in functionality and the age of onset remain elusive. A …

Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent

KA Rodriguez, E Wywial, VI Perez… - Current …, 2011 - ingentaconnect.com
Reactive oxygen species (ROS), by-products of aerobic metabolism, cause oxidative
damage to cells and tissue and not surprisingly many theories have arisen to link ROS …

[HTML][HTML] The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms

R Buffenstein, YH Edrey, T Yang, J Mele - Age, 2008 - Springer
Reactive oxygen species (ROS), inevitable byproducts of aerobic metabolism, are known to
cause oxidative damage to cells and molecules. This, in turn, is widely accepted as a pivotal …

DNA MMR systems, microsatellite instability and antioxidant activity variations in two species of wild bats: Myotis velifer and Desmodus rotundus, as possible factors …

JC Conde-Pérezprina, A Luna-López… - Age, 2012 - Springer
The accumulation of oxidative damage to biomolecules, such as DNA, is known to induce
alterations in the cell's mechanisms and structure that might lead to the aging process. DNA …

DNA MMR systems, microsatellite instability and antioxidant activity variations in two species of wild bats: Myotis velifer and Desmodus rotundus, as possible factors …

JCCP PRINA, AL LOPEZ, VYG PUERTOS, TZ SAVIN… - 2021 - repositorio.inger.gob.mx
The accumulation of oxidative damage to biomolecules, such as DNA, is known to induce
alterations in the cell's mechanisms and structure that might lead to the aging process. DNA …