Reward signals in the cerebellum: origins, targets, and functional implications

D Kostadinov, M Häusser - Neuron, 2022 - cell.com
The cerebellum has long been proposed to play a role in cognitive function, although this
has remained controversial. This idea has received renewed support with the recent …

The cerebellar cortex

C Hull, WG Regehr - Annual review of neuroscience, 2022 - annualreviews.org
The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …

Novel cerebello-amygdala connections provide missing link between cerebellum and limbic system

SJ Jung, K Vlasov, AF D'Ambra, A Parigi… - Frontiers in systems …, 2022 - frontiersin.org
The cerebellum is emerging as a powerful regulator of cognitive and affective processing
and memory in both humans and animals and has been implicated in affective disorders …

The cerebellum directly modulates the substantia nigra dopaminergic activity

S Washburn, M Oñate, J Yoshida, J Vera… - Nature …, 2024 - nature.com
Evidence of direct reciprocal connections between the cerebellum and basal ganglia has
challenged the long-held notion that these structures function independently. While …

Regulation of cerebellar network development by granule cells and their molecules

M Kim, S Jun, H Park, K Tanaka-Yamamoto… - Frontiers in Molecular …, 2023 - frontiersin.org
The well-organized cerebellar structures and neuronal networks are likely crucial for their
functions in motor coordination, motor learning, cognition, and emotion. Such cerebellar …

Eavesdropping wires: Recording activity in axons using genetically encoded calcium indicators

GJ Broussard, L Petreanu - Journal of neuroscience methods, 2021 - Elsevier
Neurons broadcast electrical signals to distal brain regions through extensive axonal arbors.
Genetically encoded calcium sensors permit the direct observation of action potential activity …

A cerebellar granule cell-climbing fiber computation to learn to track long time intervals

MG Garcia-Garcia, A Kapoor, O Akinwale, L Takemaru… - Neuron, 2024 - cell.com
In classical cerebellar learning, Purkinje cells (PkCs) associate climbing fiber (CF) error
signals with predictive granule cells (GrCs) that were active just prior (∼ 150 ms). The …

Developmental timing-dependent organization of synaptic connections between mossy fibers and granule cells in the cerebellum

T Kim, H Park, K Tanaka-Yamamoto… - Communications …, 2023 - nature.com
The long-standing hypothesis that synapses between mossy fibers (MFs) and cerebellar
granule cells (GCs) are organized according to the origins of MFs and locations of GC …

Cerebellum lineage allocation, morphogenesis and repair: impact of interplay amongst cells

AL Joyner, NS Bayin - Development, 2022 - journals.biologists.com
The cerebellum has a simple cytoarchitecture consisting of a folded cortex with three cell
layers that surrounds a nuclear structure housing the output neurons. The excitatory neurons …

A Cerebellum-Inspired Spiking Neural Model With Adapting Rate Neurons

Y Liu, R Liu, J Wang, W Chen… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
The cerebellum plays an important role in smooth and coordinated motor control. Precise
control requires the cerebellum to regulate movements in both space and time domains …