Neutrophil phenotypes and functions in cancer: A consensus statement
Neutrophils are the first responders to infection and inflammation and are thus a critical
component of innate immune defense. Understanding the behavior of neutrophils as they …
component of innate immune defense. Understanding the behavior of neutrophils as they …
Cellular mechanisms of NETosis
Neutrophils are critical to innate immunity, including host defense against bacterial and
fungal infections. They achieve their host defense role by phagocytosing pathogens …
fungal infections. They achieve their host defense role by phagocytosing pathogens …
Neutrophil intrinsic and extrinsic regulation of NETosis in health and disease
Neutrophil extracellular traps (NETs) evolved to protect the host against microbial infections
and are formed by a web-like structure of DNA that is decorated with antimicrobial effectors …
and are formed by a web-like structure of DNA that is decorated with antimicrobial effectors …
The neutrophil's role during health and disease
Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
The Role of Macrophages in Staphylococcus aureus Infection
GR Pidwill, JF Gibson, J Cole, SA Renshaw… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …
Neutrophils and NETs in modulating acute and chronic inflammation
FVS Castanheira, P Kubes - … Journal of the American Society of …, 2019 - ashpublications.org
Neutrophils are an absolutely essential part of the innate immune system, playing an
essential role in the control of infectious diseases but more recently are also being viewed …
essential role in the control of infectious diseases but more recently are also being viewed …
Neutrophil extracellular traps in immunity and disease
V Papayannopoulos - Nature Reviews Immunology, 2018 - nature.com
Neutrophils are innate immune phagocytes that have a central role in immune defence. Our
understanding of the role of neutrophils in pathogen clearance, immune regulation and …
understanding of the role of neutrophils in pathogen clearance, immune regulation and …
Inflammation, infection and venous thromboembolism
ME Colling, BE Tourdot, Y Kanthi - Circulation research, 2021 - Am Heart Assoc
The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …
recognized; yet, only in the last decades have we begun to understand the mechanisms …
Neutrophil extracellular traps: villains and targets in arterial, venous, and cancer-associated thrombosis
Recent studies have demonstrated a role of neutrophils in both venous and arterial
thrombosis. A key prothrombotic feature of neutrophils is their ability to release web-like …
thrombosis. A key prothrombotic feature of neutrophils is their ability to release web-like …
Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases
M Herre, J Cedervall, N Mackman… - Physiological …, 2023 - journals.physiology.org
Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …