Underlying features of prostate cancer—statistics, risk factors, and emerging methods for its diagnosis

CV Berenguer, F Pereira, JS Câmara, JAM Pereira - Current Oncology, 2023 - mdpi.com
Prostate cancer (PCa) is the most frequently occurring type of malignant tumor and a leading
cause of oncological death in men. PCa is very heterogeneous in terms of grade …

[HTML][HTML] Hereditary cancer syndromes

EN Imyanitov, ES Kuligina, AP Sokolenko… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hereditary cancer syndromes (HCSs) are arguably the most frequent category of Mendelian
genetic diseases, as at least 2% of presumably healthy subjects carry highly-penetrant …

Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer

CJ Creighton, F Zhang, Y Zhang, P Castro, R Hu… - Epigenetics, 2023 - Taylor & Francis
African American (AA) men have the highest incidence and mortality rate from Prostate
cancer (PCa) than any other racial/ethnic group. To date, PCa genomic studies have largely …

Innovative Drug Modalities for the Treatment of Advanced Prostate Cancer

M Capuozzo, M Santorsola, M Ianniello, F Ferrara… - Diseases, 2024 - mdpi.com
Prostate cancer, a prevalent malignancy affecting the prostate gland, is a significant global
health concern. Androgen-deprivation therapy (ADT) has proven effective in controlling …

Germline Mutations and Ancestry in Prostate Cancer

E Bataba, K Babcock, KA Isensee, B Eldhose… - Current oncology …, 2024 - Springer
Abstract Purpose of Review Prostate cancer is the most frequently diagnosed non-
cutaneous malignancy of men in the USA; notably, the incidence is higher among men of …

Development of PARP Inhibitors in Targeting Castration-Resistant Prostate Cancer

KW Mouw, AD Choudhury - Targeting the DNA Damage Response for …, 2023 - Springer
Prostate cancer is a genetically heterogenous disease and a subset of prostate tumors
harbor alterations in DNA damage and repair (DDR) genes. Prostate tumor DDR gene …

[HTML][HTML] Efficacy of national comprehensive cancer Network guidelines in identifying pathogenic germline variants among unselected patients with prostate cancer …

N Shore, M Gazi, C Pieczonka, S Heron, R Modh… - European Urology …, 2023 - Elsevier
Abstract Background Prostate cancer (PCa) patients with pathogenic/likely pathogenic
germline variants (PGVs) in cancer predisposition genes may be eligible for US Food and …

[PDF][PDF] Efficacy of National Comprehensive Cancer Network Guidelines in Identifying Pathogenic Germline Variants Among Unselected Patients with Prostate Cancer …

G Giannarini, A Vickers - 2023 - researchgate.net
Abstract Background: Prostate cancer (PCa) patients with pathogenic/likely pathogenic
germline variants (PGVs) in cancer predisposition genes may be eligible for US Food and …

Urinary Metabolomic Fingerprints as a Powerful Tool for the Next Generation of Prostate Cancer Diagnosis

CV Berenguer - 2022 - search.proquest.com
Prostate cancer (PCa) remains the most frequent malignant tumour and a leading cause of
oncological death in men, despite the spectacular advances in molecular medicine …