[HTML][HTML] Toward a global virus genomic surveillance network
The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating
its utility for public health. Now, we must harness the momentum that led to increased …
its utility for public health. Now, we must harness the momentum that led to increased …
Progress and challenges in virus genomic epidemiology
Genomic epidemiology, which links pathogen genomes with associated metadata to
understand disease transmission, has become a key component of outbreak response …
understand disease transmission, has become a key component of outbreak response …
Clade I mpox virus genomic diversity in the Democratic Republic of the Congo, 2018–2024: predominance of zoonotic transmission
E Kinganda-Lusamaki, A Amuri-Aziza… - Cell, 2024 - cell.com
Recent reports raise concerns on the changing epidemiology of mpox in the Democratic
Republic of the Congo (DRC). High-quality genomes were generated for 337 patients from …
Republic of the Congo (DRC). High-quality genomes were generated for 337 patients from …
Acute SARS-CoV-2 infections harbor limited within-host diversity and transmit via tight transmission bottlenecks
The emergence of divergent SARS-CoV-2 lineages has raised concern that novel variants
eliciting immune escape or the ability to displace circulating lineages could emerge within …
eliciting immune escape or the ability to displace circulating lineages could emerge within …
Sensitive poliovirus detection using nested PCR and nanopore sequencing: A prospective validation study
AG Shaw, TK Mampuela, EL Lofiko, C Pratt… - Nature …, 2023 - nature.com
Timely detection of outbreaks is needed for poliovirus eradication, but gold standard
detection in the Democratic Republic of the Congo takes 30 days (median). Direct molecular …
detection in the Democratic Republic of the Congo takes 30 days (median). Direct molecular …
A pan-African pathogen genomics data sharing platform to support disease outbreaks
A pan-African pathogen genomics data sharing platform to support disease outbreaks | Nature
Medicine Skip to main content Thank you for visiting nature.com. You are using a browser …
Medicine Skip to main content Thank you for visiting nature.com. You are using a browser …
Approaches and challenges to inferring the geographical source of infectious disease outbreaks using genomic data
Genomic data hold increasing potential in the elucidation of transmission dynamics and
geographical sources of infectious disease outbreaks. Phylogeographic methods that use …
geographical sources of infectious disease outbreaks. Phylogeographic methods that use …
[HTML][HTML] A review of broadly protective monoclonal antibodies to treat Ebola virus disease
P Rijal, FR Donnellan - Current Opinion in Virology, 2023 - Elsevier
Highlights•mAbs mixture targeting independent epitopes are better therapeutics.•Optimizing
antibody efficacy: in vitro maturation, afucosylation, Fc modifications.•Monitoring of natural …
antibody efficacy: in vitro maturation, afucosylation, Fc modifications.•Monitoring of natural …
The impact of sampling bias on viral phylogeographic reconstruction
Genomic epidemiology plays an ever-increasing role in our understanding of and response
to the spread of infectious pathogens. Phylogeography, the reconstruction of the historical …
to the spread of infectious pathogens. Phylogeography, the reconstruction of the historical …
Filoviruses: scientific gaps and prototype pathogen recommendation
LC Dupuy, CF Spiropoulou, JS Towner… - The Journal of …, 2023 - academic.oup.com
Viruses in the family Filoviridae, including the commonly known Ebola (EBOV) and Marburg
(MARV) viruses, can cause severe hemorrhagic fever in humans and nonhuman primates …
(MARV) viruses, can cause severe hemorrhagic fever in humans and nonhuman primates …