Atroposelective total synthesis of axially chiral biaryl natural products
G Bringmann, T Gulder, TAM Gulder… - Chemical …, 2011 - ACS Publications
Intellectual curiosity has always been one of the major driving forces leading to new
advances in chemistry. At the onset of the 20th century, the fact that biaryls could be optically …
advances in chemistry. At the onset of the 20th century, the fact that biaryls could be optically …
Fruitful decade for antileishmanial compounds from 2002 to late 2011
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …
N, C-Coupled naphthylisoquinoline alkaloids: a versatile new class of axially chiral natural products
N Tajuddeen, G Bringmann - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to April 2021 During the past decades, a plethora of natural products with
restricted rotation about a biaryl axis have been discovered, among them the …
restricted rotation about a biaryl axis have been discovered, among them the …
Identification of multiple cellular uptake pathways of polystyrene nanoparticles and factors affecting the uptake: Relevance for drug delivery systems
R Firdessa, TA Oelschlaeger, H Moll - European journal of cell biology, 2014 - Elsevier
Nanoparticles may address challenges by human diseases through improving diagnosis,
vaccination and treatment. The uptake mechanism regulates the type of threat a particle …
vaccination and treatment. The uptake mechanism regulates the type of threat a particle …
Dimeric naphthylisoquinoline alkaloids: polyketide-derived axially chiral bioactive quateraryls
BK Lombe, D Feineis, G Bringmann - Natural Product Reports, 2019 - pubs.rsc.org
Covering: up to April 2019 Dimeric naphthylisoquinoline (NIQ) alkaloids are an emerging
group of structurally, biosynthetically, and pharmacologically intriguing natural products, as …
group of structurally, biosynthetically, and pharmacologically intriguing natural products, as …
Korupensamine A, but not its atropisomer, korupensamine B, inhibits SARS-CoV-2 in vitro by targeting its main protease (Mpro)
By combining docking and molecular dynamics simulations, we explored a library of 65
mostly axially chiral naphthylisoquinoline alkaloids and their analogues, with most different …
mostly axially chiral naphthylisoquinoline alkaloids and their analogues, with most different …
Marilines A–C: Novel Phthalimidines from the Sponge‐Derived Fungus Stachylidium sp.
C Almeida, Y Hemberger, SM Schmitt… - … A European Journal, 2012 - Wiley Online Library
A marine‐derived fungus of the genus Stachylidium was isolated from the sponge
Callyspongia cf. C. flammea. Chemical investigation of the bioactive fungal extract led to the …
Callyspongia cf. C. flammea. Chemical investigation of the bioactive fungal extract led to the …
New antileishmanial candidates and lead compounds
JV Richard, KA Werbovetz - Current opinion in chemical biology, 2010 - Elsevier
Although miltefosine and paromomycin were registered as clinical agents against visceral
leishmaniasis in the last decade, the antileishmanial drug arsenal still requires …
leishmaniasis in the last decade, the antileishmanial drug arsenal still requires …
Asian Ancistrocladus Lianas as Creative Producers of Naphthylisoquinoline Alkaloids
D Feineis, G Bringmann - Ancistrocladus Naphthylisoquinoline Alkaloids, 2023 - Springer
This book describes a unique class of secondary metabolites, the mono-and dimeric
naphthylisoquinoline alkaloids. They occur in lianas of the paleotropical Ancistrocladaceae …
naphthylisoquinoline alkaloids. They occur in lianas of the paleotropical Ancistrocladaceae …
Total Synthesis of the N,C-Coupled Naphthylisoquinoline Alkaloids Ancistrocladinium A and B and Related Analogues
G Bringmann, T Gulder, B Hertlein… - Journal of the …, 2010 - ACS Publications
The N, C-coupled naphthyldihydroisoquinoline alkaloids ancistrocladinium A (3) and B (4),
which possess an unprecedented iminium-aryl axis and show high in vitro antileishmanial …
which possess an unprecedented iminium-aryl axis and show high in vitro antileishmanial …