In this article, the upgrading process of the structure-based virtual screening (SBVS) protocol
targeting acetylcholinesterase (AChE) previously published in 2017 is presented. The …

Previous studies has shown that estrogen receptor alpha that binds to estrogen may
increase cancer cell proliferation, thus estrogen receptor alpha can be targeted to cure …

One of well-established biological activities for chalcone derivatives is as
acetylcholinesterase inhibitors, which can be developed for the therapy of Alzheimer's …

Objective: The objective of this study is to Construct predictive unbiased structure-based
virtual screening (SBVS) protocols to identify potent ligands for estrogen receptor alpha by …

One of the key targets in the drug development for potential Alzheimer's disease (AD)
therapeutics is the search for acetylcholinesterase enzyme (AChE) inhibitors. Very recently …

Identification of molecular determinants of receptor-ligand binding could significantly
increase the quality of structure-based virtual screening protocols. In turn, drug design …

Abstract Employing ensemble Protein-Ligand Interaction Fingerprints (ensPLIF) as
descriptors in post retrospective Structure-Based Virtual Screening (SBVS) campaigns …

Abstract Structure-Based Virtual Screening (SBVS) campaigns employing Protein-Ligand
Interaction Fingerprints (PLIF) identification have served as a powerful strategy in fragments …

ABSTRACT By employing Databases of Useful Decoys (DUD) and its enhanced version
(DUD-E), several attempts to construct validated Structure-based Virtual Screening (SBVS) …

Tulisan untuk Mata Kuliah Kimia Medisinal dan Rancangan Obat dan dapat digunakan
untuk materi-materi perkuliahan terkait di bidang Ilmu Farmasi pada khususnya dan Ilmu …