Recent investigations into synthesis and pharmacological activities of phenoxy acetamide and its derivatives (chalcone, indole and quinoline) as possible therapeutic …
FH Al-Ostoot, Zabiulla, S Salah, SA Khanum - Journal of the Iranian …, 2021 - Springer
Medicinal chemistry can rightfully be regarded as a cornerstone in the public health of our
modern society that combines chemistry and pharmacology with the aim of designing and …
modern society that combines chemistry and pharmacology with the aim of designing and …
Synthesis, crystal structure, DFT calculations, Hirshfeld surface analysis, energy frameworks, molecular dynamics and docking studies of novel isoxazolequinoxaline …
Quinoxaline derivatives with the molecular formula [C 8 H 6 N 2] also named
benzopyrazines, which are a valuable class of heterocyclic compounds useful for their …
benzopyrazines, which are a valuable class of heterocyclic compounds useful for their …
[HTML][HTML] Molecular docking, synthesis and antimicrobial evaluation of metal complexes with Schiff base
The appearance of resistant bacteria was found to reduce the efficiency of antimicrobial
therapies with the current antibiotics, thereby increasing the need for more efficient drugs for …
therapies with the current antibiotics, thereby increasing the need for more efficient drugs for …
Design-based synthesis, molecular docking analysis of an anti-inflammatory drug, and geometrical optimization and interaction energy studies of an indole acetamide …
The new indole acetamide, N-(2-(2-(4-Chlorophenoxy) acetamido) phenyl)-2-carboxamide-
1H-indole (5) has been synthesized with good yield by stirring the compound N-(2 …
1H-indole (5) has been synthesized with good yield by stirring the compound N-(2 …
Design, docking, synthesis, and characterization of novel N'(2-phenoxyacetyl) nicotinohydrazide and N'(2-phenoxyacetyl) isonicotinohydrazide derivatives as anti …
Inflammation is the complex biological response of vascular tissues, which is partly
determined by prostaglandins (PLA 2). The cyclooxygenase (COX) enzyme exists in two …
determined by prostaglandins (PLA 2). The cyclooxygenase (COX) enzyme exists in two …
Synthesis, structure elucidation, Hirshfeld surface analysis, energy frameworks and DFT studies of novel ethyl 2-(5-methyl-2-oxopyridin-N-yl) acetate (OPA)
KM Chandini, FH Al-Ostoot, TN Lohith… - Journal of Molecular …, 2022 - Elsevier
Abstract The compound ethyl 2-(5-methyl-2-oxopyridin-N-yl) acetate (OPA) has been
synthesized and characterized by 1 H, 13 C NMR and mass spectra. The molecular structure …
synthesized and characterized by 1 H, 13 C NMR and mass spectra. The molecular structure …
Spectroscopic, density functional theory and molecular docking studies of zinc (II) and nickel (II) complexes of Nˈ-(Furan-2-ylmethylene) furan-2-carbohydrazide as …
PS Mbatu, GM Toh-Boyo, JN Ghogomu, EN Nfor… - Journal of Molecular …, 2024 - Elsevier
A furoic acid hydrazide derivative C 10 H 8 N 2 O 3 (L), its nickel (II) and zinc (II) complexes
(Ni (L) 2 and Zn (L) 2 respectively have been synthesized. The prepared ligand and its metal …
(Ni (L) 2 and Zn (L) 2 respectively have been synthesized. The prepared ligand and its metal …
Synthesis, crystal structure characterization, DFT calculations, Hirshfeld surface analysis and 3D energy frameworks of triazole pyridazine derivatives: Theoretical and …
Recently, pyridazine derivatives have shown considerable biological properties such as anti-
tumor and anti-inflammatory activity. The studied compounds 6-chloro-3-[(4-methylphenoxy) …
tumor and anti-inflammatory activity. The studied compounds 6-chloro-3-[(4-methylphenoxy) …
Synthesis, structural characterization, and DFT studies of anti-cancer drug N-(2-Aminophenyl)-2-(4-bromophenoxy) acetamide
SN Chandana, FH Al-Ostoot, YHE Mohammed… - Heliyon, 2021 - cell.com
Drug design is an integrated and developing system that portends an era of a novel and
safe tailored drugs. It involves studying the effects of biologically active synthetic, semi …
safe tailored drugs. It involves studying the effects of biologically active synthetic, semi …
Synthesis, structural analysis, Hirshfeld surface analysis, DFT calculations, in vitro and docking study on antioxidant activity of 6-chloro-3-[(4-methylphenoxy) methyl] …
HH Sallam, YHE Mohammed, G DV… - … Crystals and Liquid …, 2021 - Taylor & Francis
Pyridazine nuclei are essential elements of many natural and synthetic compounds with
important biological activities. NMR and IR, as well as studies of mass spectrum, were …
important biological activities. NMR and IR, as well as studies of mass spectrum, were …