A review of the effects of ticagrelor on adenosine concentration and its clinical significance
Background Ticagrelor is an oral antiplatelet drug that can reversibly bind to the platelet
P2Y12 receptor. Ticagrelor is metabolized mainly by CYP3A4 and produces a rapid blood …
P2Y12 receptor. Ticagrelor is metabolized mainly by CYP3A4 and produces a rapid blood …
[HTML][HTML] Antiplatelet therapy after percutaneous coronary intervention
Antiplatelet therapy is key to reducing local thrombotic complications and systemic
ischaemic events among patients undergoing percutaneous coronary interventions (PCI) …
ischaemic events among patients undergoing percutaneous coronary interventions (PCI) …
Timing, Selection, Modulation, and Duration of P2Y12 Inhibitors for Patients With Acute Coronary Syndromes Undergoing PCI
D Capodanno, DJ Angiolillo - Cardiovascular Interventions, 2023 - jacc.org
Dual antiplatelet therapy with aspirin and the oral P2Y12 inhibitor clopidogrel as the
cornerstone of treatment for patients with an acute coronary syndrome (ACS) undergoing …
cornerstone of treatment for patients with an acute coronary syndrome (ACS) undergoing …
Comparative effects of guided vs. potent P2Y12 inhibitor therapy in acute coronary syndrome: a network meta-analysis of 61 898 patients from 15 randomized trials
Aims Guidelines recommend the use of potent P2Y12 inhibitors over clopidogrel for the
reduction of ischaemic events in patients with acute coronary syndrome (ACS). However …
reduction of ischaemic events in patients with acute coronary syndrome (ACS). However …
Treatment timing and the effects of rhythm control strategy in patients with atrial fibrillation: nationwide cohort study
Objective To investigate whether the results of a rhythm control strategy differ according to
the duration between diagnosis of atrial fibrillation and treatment initiation. Design …
the duration between diagnosis of atrial fibrillation and treatment initiation. Design …
Comparative effectiveness and safety between apixaban, dabigatran, edoxaban, and rivaroxaban among patients with atrial fibrillation: a multinational population …
Background: Current guidelines recommend using direct oral anticoagulants (DOACs) over
warfarin in patients with atrial fibrillation (AF), but head-to-head trial data do not exist to …
warfarin in patients with atrial fibrillation (AF), but head-to-head trial data do not exist to …
Association between proton pump inhibitor use and gastric cancer: a population-based cohort study using two different types of nationwide databases in Korea
Objective The association between proton pump inhibitor (PPI) use and gastric cancer
related to Helicobacter pylori eradication has not been fully investigated in geographical …
related to Helicobacter pylori eradication has not been fully investigated in geographical …
Scalable infrastructure supporting reproducible nationwide healthcare data analysis toward FAIR stewardship
Transparent and FAIR disclosure of meta-information about healthcare data and
infrastructure is essential but has not been well publicized. In this paper, we provide a …
infrastructure is essential but has not been well publicized. In this paper, we provide a …
Genetic testing in patients undergoing percutaneous coronary intervention: rationale, evidence and practical recommendations
Introduction Clopidogrel is the most frequently utilized P2Y12 inhibitor and is characterized
by broad interindividual response variability resulting in impaired platelet inhibition and …
by broad interindividual response variability resulting in impaired platelet inhibition and …
[HTML][HTML] Platelet function and genotype after DES implantation in East Asian patients: rationale and characteristics of the PTRG-DES consortium
Purpose Platelet function test (PFT) results and genotype hold unique prognostic
implications in East Asian patients. The aim of the PTRG-DES (Platelet function and …
implications in East Asian patients. The aim of the PTRG-DES (Platelet function and …