Previously, we have reported on a zwitterionic cocrystal of diclofenac acid and L-proline.
However, the solubility of this multicomponent crystal was still lower than that of diclofenac …

This research dealt with the multicomponent crystal developed from diclofenac potassium
and l-proline to improve the pharmaceutical performance of this anti-inflammatory drug …

Viruses are the current big enemy of the world's healthcare systems. As the small infector
causes various deadly diseases, from influenza and HIV to COVID-19, the virus continues to …

A cocrystal of mefenamic acid (MA)-nicotinamide (NA) has been reported to increase the
solubility of MA, but it still does not exceed the solubility of sodium mefenamate (SM) …

Objective: This study aimed to improve the solubility of Ketoprofen, a non-steroidal anti-
inflammatory drug (NSAID) that belongs to the Biopharmaceutical Classification System …

Every" entity" or compound has physical and chemical properties as references for the
synthesis and determination of the entity's structure. Thermodynamically, solid-state is the …

The sodium salt of theophylline is ferrocenylmethylated at N7 in water using [FcCH2NMe3] I.
Further alkylation at N9 with various reagents and under different conditions was however …

Reaction of theophylline with [Rh 2 (μ-OAc) 2 (μ-HNOCCF 3) 2] gave [Rh 2 (μ-OAc) 2 (μ-
HNOCCF 3) 2 (theophylline) 2]· 6H 2 O (1), whose crystal structure was determined by …

Objective: Formation of clindamycin hydrochloride (clindamycin HCl) in monohydrate-
ethanolate from the recrystallization process with ethanol–water (5: 2) has been reported a …

Objective: The objective of the current study was to develop and validate a novel RP-HPLC
method for determination of bamifylline hydrochloride in pharmaceutical dosage form …