Markers of central inflammation in major depressive disorder: a systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission …

D Enache, CM Pariante, V Mondelli - Brain, behavior, and immunity, 2019 - Elsevier
Background Increased peripheral inflammation has been consistently reported in patients
with major depressive disorder (MDD). However, only few studies have explored markers of …

The emerging tale of microglia in psychiatric disorders

R Rahimian, M Wakid, LA O'Leary… - … & Biobehavioral Reviews, 2021 - Elsevier
As the professional phagocytes of the brain, microglia orchestrate the immunological
response and play an increasingly important role in maintaining homeostatic brain functions …

[HTML][HTML] Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes

M Maitra, H Mitsuhashi, R Rahimian, A Chawla… - Nature …, 2023 - nature.com
Major depressive disorder (MDD) is a common, heterogenous, and potentially serious
psychiatric illness. Diverse brain cell types have been implicated in MDD etiology …

[HTML][HTML] A specific inflammatory profile underlying suicide risk? Systematic review of the main literature findings

G Serafini, VM Parisi, A Aguglia, A Amerio… - International journal of …, 2020 - mdpi.com
Consistent evidence indicates the association between inflammatory markers and suicidal
behavior. The burden related to immunological differences have been widely documented in …

[HTML][HTML] The relationship between chronic immune response and neurodegenerative damage in long COVID-19

JP Elizalde-Díaz, CL Miranda-Narváez… - Frontiers in …, 2022 - frontiersin.org
In the past two years, the world has faced the pandemic caused by the severe acute
respiratory syndrome 2 coronavirus (SARS-CoV-2), which by August of 2022 has infected …

Sleep complaints are associated with increased suicide risk independently of psychiatric disorders: results from a national 3-year prospective study

PA Geoffroy, MA Oquendo, P Courtet, C Blanco… - Molecular …, 2021 - nature.com
Prior research suggests that sleep disturbances are associated with increased risk of
suicide. However, sleep disturbances are associated with a wide range of psychiatric …

[HTML][HTML] Non-coding RNAs in depression: Promising diagnostic and therapeutic biomarkers

Y Shi, Q Wang, R Song, Y Kong, Z Zhang - EBioMedicine, 2021 - thelancet.com
Abstract Non-coding RNAs (ncRNAs), including microRNAs, circular RNAs, and long non-
coding RNAs, are important regulators of normal biological processes and their abnormal …

Exploiting circulating MicroRNAs as biomarkers in psychiatric disorders

B Roy, Y Yoshino, L Allen, K Prall, G Schell… - Molecular diagnosis & …, 2020 - Springer
Non-invasive peripheral biomarkers play a significant role in both disease diagnosis and
progression. In the past few years, microRNA (miRNA) expression changes in circulating …

Large-scale transcriptomics studies provide insight into sex differences in depression

ML Seney, J Glausier, E Sibille - Biological psychiatry, 2022 - Elsevier
Major depressive disorder (MDD) is a leading cause of disability, affecting more than 300
million people worldwide. We first review the well-known sex difference in incidence of …

The role of inflammation in the pathophysiology of depression and suicidal behavior: implications for treatment

G Serafini, A Costanza, A Aguglia, A Amerio… - Medical …, 2023 - medical.theclinics.com
Neuropsychiatric illnesses represent a significant cause of mortality worldwide, 1 with more
than 30% increase in recent years. Among these conditions with high socioeconomic cost …