Physiological Approach to Assessment of Acid–Base Disturbances | New England Journal of
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Acute metabolic acidosis is associated with increased morbidity and mortality because of its
depressive effects on cardiovascular function, facilitation of cardiac arrhythmias, stimulation …

Cancer immunotherapies, such as immune checkpoint blockade or adoptive T-cell transfer,
can lead to durable responses in the clinic, but response rates remain low due to undefined …

La reanimación con fluidos es esencial para la supervivencia del paciente crítico en shock,
independientemente de la causa que lo origine. Hoy en día disponemos de diversos …

Sepsis is a common cause of death, but outcomes in individual patients are difficult to
predict. Elucidating the molecular processes that differ between sepsis patients who survive …

Objectives: Hyperchloremia is frequently observed in critically ill patients in the ICU. Our
study aimed to examine the association of serum chloride (Cl) levels with hospital mortality …

Background Acute kidney injury and hyperchloremia are commonly present in critically ill
septic patients. Our study goal was to evaluate the association of hyperchloremia and acute …

Lactic acidosis is a very common biological issue for shock patients. Experimental data
clearly demonstrate that metabolic acidosis, including lactic acidosis, participates in the …

The present review of fluid therapy studies using balanced solutions versus isotonic saline
fluids (both crystalloids and colloids) aims to address recent controversy in this topic. The …

Neutrophil extracellular traps (NETs) play a pivotal role in the innate immune defense, as
well as in the pathophysiology of various inflammatory disease conditions. Two major types …