Ankylosing spondylitis (AS) is a common immune‐mediated inflammatory arthritis with a
strong genetic predisposition. We review recent data from genetic and animal studies …

Axial spondyloarthritis (axial-SpA) is a multifactorial disease characterized by inflammation
in sacroiliac joints and spine, bone reabsorption, and aberrant bone deposition, which may …

Spondyloarthritis (SpA) represents a family of inflammatory diseases of the spine and
peripheral joints. Ankylosing spondylitis (AS) is the prototypic form of SpA in which …

Rheumatoid arthritis (RA) and other autoimmune inflammatory diseases are examples of
imbalances within the immune system (disrupted homeostasis) that arise from the effects of …

Purpose Patients with heterozygous gain-of-function (GOF) mutations in STAT1 frequently
exhibit chronic mucocutaneous candidiasis (CMC), immunodeficiency and autoimmune …

Purpose To investigate the therapeutic effectiveness and safety of Janus kinase 1 inhibitor
upadacitinib in adolescent patients with atopic dermatitis (AD). Patients and Methods This …

Spondyloarthritis (SpA) is a heterogeneous group of chronic inflammatory diseases of
unknown etiology. Over time, the plethora of cellular elements involved in its pathogenesis …

Objective AS is a rheumatic disease characterized by chronic inflammation and bony
ankylosis. This study was to evaluate whether a signal transducer and activator of …

Background. Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by
sacroiliitis and spinal rigidity of the axial joints. The role of oxidative stress and increased …

Background Ankylosing spondylitis (AS) is a progressive rheumatic disease and studies
reveal that the immune system is critical for the pathogenesis of AS. In the present study …