Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Inflammation is a key driver in many pathological conditions such as allergy, cancer,
Alzheimer's disease, and many others, and the current state of available drugs prompted …

Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Foot ulcers are one of the most common and severe complication of diabetes mellitus with
significant resultant morbidity and mortality. Multiple factors impair wound healing include …

The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by NFE2L2) and its
principal negative regulator, the E3 ligase adaptor Kelch-like ECH-associated protein 1 …

Wound management in diabetic patient is of an extreme clinical and social concern. The
delayed and impaired healing makes it more critical for research focus. The research on …

The transcription factor NRF2 is the master regulator of the cellular antioxidant response.
Though recognized originally as a target of chemopreventive compounds that help prevent …

Impaired wound healing and ulcer complications are a leading cause of death in diabetic
patients. In this study, we report the design and synthesis of a cyclometalated iridium (III) …

Diabetic foot ulcers (DFU) increase the risks of infection and amputation in patients with
diabetes mellitus (DM). The impaired function and senescence of endothelial progenitor …

Poor wound healing can seriously affect the health of patients with diabetes and result in a
heavy medical burden. Recently, exosomes have been considered the key substances …