Ion-exchange chromatography coupled to mass spectrometry in life science, environmental, and medical research

JB Ngere, KH Ebrahimi, R Williams, E Pires… - Analytical …, 2023 - ACS Publications
Ion-exchange chromatography (IEC) is a chromatographic technique commonly used for the
separation of ions and ionizable molecules. Its direct coupling with mass spectrometry has …

Applications of ion chromatography in urine analysis: a review

J Pang, Y Huang, Y Liu, W Huang - Journal of Chromatography A, 2023 - Elsevier
Ion chromatography (IC) plays a crucial role in urine analysis for diverse medical diagnoses.
This paper reviews a comprehensive investigation into urine pretreatment techniques, as …

A modified QuEChERS-DART-MS/MS technique for high-throughput detection of organophosphate nerve agent hydrolysis products in environmental samples

G Qu, B Chen, S Liu, Q Zhang, Y Yang, Q Fu - Journal of Analysis and …, 2023 - Springer
Organophosphate nerve agents (OPNAs) are lethal chemical weapons (CWs) which
hydrolyze rapidly to alkyl phosphate compounds in the environment. The identification of …

Chromatographic analysis of chemical warfare agents and their metabolites in biological samples

Z Witkiewicz, S Neffe - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
The objective of this study is to present and critically analyze the current state of knowledge
on the chromatographic analysis of chemical warfare agents (CWAs) and their metabolites …

Analysis of the precursors, simulants and degradation products of chemical warfare agents

Z Witkiewicz, S Neffe, E Sliwka… - Critical Reviews in …, 2018 - Taylor & Francis
Recent advances in analysis of precursors, simulants and degradation products of chemical
warfare agents (CWA) are reviewed. Fast and reliable analysis of precursors, simulants and …

A review on analysis methods for nerve agent hydrolysis products

IS Che Sulaiman, BW Chieng, FE Pojol, KK Ong… - Forensic …, 2020 - Springer
Purpose This review article provides an overview of the background of nerve agents (NAs)
and their hydrolysis products. The analytical techniques that are used for the analysis of …

Simultaneous determination of organophosphorus nerve agent markers in urine by IC-MS/MS using anion-exchange solid-phase extraction

T Baygildiev, M Vokuev, R Ogorodnikov… - … of Chromatography B, 2019 - Elsevier
In this study a comprehensive approach for determination of low molecular
organophosphorus nerve agent markers–highly polar alkylphosphonic acids and much less …

Novel adsorbents for the determination of amino acids in soil extracts by hydrophilic interaction liquid chromatography with mass spectrometric detection

NY Chikurova, AV Gorbovskaia, AN Stavrianidi… - Journal of Analytical …, 2023 - Springer
Adsorbents based on various substrates—silica and a copolymer of styrene with
divinylbenzene—are developed for the determination of amino acids by hydrophilic …

Revealing nitrogenous VX metabolites and the whole-molecule VX metabolism in the urine of guinea pigs

PY Jiang, L Yuan, DX Liu, HL Yu, XJ Bi, Q Lv… - Journal of Hazardous …, 2024 - Elsevier
VX, a well-known organophosphorus nerve agent (OPNA), poses a significant threat to
public safety if employed by terrorists. Obtaining complete metabolites is critical to …

Magnetic mesoporous Fe 3 O 4@ n SiO 2@ m SiO 2 nanoparticles for high-throughput mass spectrometry detection of hydrolyzed products of organophosphorus …

G Qu, Y Zhao, Q Zhang, J Wu, X Li, Y Yang, S Liu - Analytical Methods, 2024 - pubs.rsc.org
Rapid and accurate detection of hydrolyzed products of organophosphorus nerve agents
(OPNAs) is an important method to effectively confirm the use of these agents. OPNAs are …