The maternal-to-zygotic transition revisited
The development of animal embryos is initially directed by maternal gene products. Then,
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …
P bodies and the control of mRNA translation and degradation
R Parker, U Sheth - Molecular cell, 2007 - cell.com
Recent results indicate that many untranslating mRNAs in somatic eukaryotic cells assemble
into related mRNPs that accumulate in specific cytoplasmic foci referred to as P bodies …
into related mRNPs that accumulate in specific cytoplasmic foci referred to as P bodies …
[HTML][HTML] RNA granules
P Anderson, N Kedersha - The Journal of cell biology, 2006 - ncbi.nlm.nih.gov
Cytoplasmic RNA granules in germ cells (polar and germinal granules), somatic cells (stress
granules and processing bodies), and neurons (neuronal granules) have emerged as …
granules and processing bodies), and neurons (neuronal granules) have emerged as …
[HTML][HTML] Inactivation of conserved C. elegans genes engages pathogen-and xenobiotic-associated defenses
The nematode C. elegans is attracted to nutritious bacteria and is repelled by pathogens
and toxins. Here we show that RNAi and toxin-mediated disruption of core cellular activities …
and toxins. Here we show that RNAi and toxin-mediated disruption of core cellular activities …
P bodies: at the crossroads of post-transcriptional pathways
A Eulalio, I Behm-Ansmant, E Izaurralde - Nature reviews Molecular …, 2007 - nature.com
Post-transcriptional processes have a central role in the regulation of eukaryotic gene
expression. Although it has been known for a long time that these processes are functionally …
expression. Although it has been known for a long time that these processes are functionally …
RNA granules in germ cells
E Voronina, G Seydoux… - Cold Spring …, 2011 - cshperspectives.cshlp.org
“Germ granules” are cytoplasmic, nonmembrane-bound organelles unique to germline.
Germ granules share components with the P bodies and stress granules of somatic cells, but …
Germ granules share components with the P bodies and stress granules of somatic cells, but …
[HTML][HTML] The control of mRNA decapping and P-body formation
TM Franks, J Lykke-Andersen - Molecular cell, 2008 - cell.com
mRNA decapping is a critical step in eukaryotic cytoplasmic mRNA turnover. Cytoplasmic
mRNA decapping is catalyzed by Dcp2 in conjunction with its coactivator Dcp1 and is …
mRNA decapping is catalyzed by Dcp2 in conjunction with its coactivator Dcp1 and is …
Pathway to totipotency: lessons from germ cells
G Seydoux, RE Braun - Cell, 2006 - cell.com
Oocytes and sperm are some of the most differentiated cells in our bodies, yet they generate
all cell types after fertilization. Accumulating evidence suggests that this extraordinary …
all cell types after fertilization. Accumulating evidence suggests that this extraordinary …
Staufen-and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies
SA Barbee, PS Estes, AM Cziko, J Hillebrand… - Neuron, 2006 - cell.com
Local control of mRNA translation modulates neuronal development, synaptic plasticity, and
memory formation. A poorly understood aspect of this control is the role and composition of …
memory formation. A poorly understood aspect of this control is the role and composition of …
Universal Features of Post-Transcriptional Gene Regulation Are Critical for Plasmodium Zygote Development
A universal feature of metazoan sexual development is the generation of oocyte P granules
that withhold certain mRNA species from translation to provide coding potential for proteins …
that withhold certain mRNA species from translation to provide coding potential for proteins …