Drosophila as a model to study obesity and metabolic disease
LP Musselman, RP Kühnlein - Journal of Experimental …, 2018 - journals.biologists.com
Excess adipose fat accumulation, or obesity, is a growing problem worldwide in terms of
both the rate of incidence and the severity of obesity-associated metabolic disease. Adipose …
both the rate of incidence and the severity of obesity-associated metabolic disease. Adipose …
Glucose as a major antioxidant: when, what for and why it fails?
A human organism depends on stable glucose blood levels in order to maintain its
metabolic needs. Glucose is considered to be the most important energy source, and …
metabolic needs. Glucose is considered to be the most important energy source, and …
[PDF][PDF] Sugar-induced obesity and insulin resistance are uncoupled from shortened survival in Drosophila
E van Dam, LAG van Leeuwen, E Dos Santos, J James… - Cell metabolism, 2020 - cell.com
High-sugar diets cause thirst, obesity, and metabolic dysregulation, leading to diseases
including type 2 diabetes and shortened lifespan. However, the impact of obesity and water …
including type 2 diabetes and shortened lifespan. However, the impact of obesity and water …
Drosophila melanogaster as a Versatile Model Organism in Food and Nutrition Research
S Staats, K Lüersen, AE Wagner… - Journal of agricultural …, 2018 - ACS Publications
Drosophila melanogaster has been widely used in the biological sciences as a model
organism. Drosophila has a relatively short life span of 60–80 days, which makes it attractive …
organism. Drosophila has a relatively short life span of 60–80 days, which makes it attractive …
Measurement of solid food intake in Drosophila via consumption-excretion of a dye tracer
BC Shell, RE Schmitt, KM Lee, JC Johnson… - Scientific reports, 2018 - nature.com
Although the Drosophila melanogaster (fly) model is a popular platform for investigating diet-
related phenomena, it can be challenging to measure the volume of agar-based food media …
related phenomena, it can be challenging to measure the volume of agar-based food media …
Drosophila insulin‐like peptides: from expression to functions – a review
U Semaniuk, V Piskovatska… - Entomologia …, 2021 - Wiley Online Library
Insulin‐like peptides (ILPs) belong to the insulin superfamily and act as hormones,
neuromediators, and growth factors during the post‐embryonic life‐cycle stages of insects …
neuromediators, and growth factors during the post‐embryonic life‐cycle stages of insects …
Random forest classification for predicting lifespan-extending chemical compounds
S Kapsiani, BJ Howlin - Scientific reports, 2021 - nature.com
Ageing is a major risk factor for many conditions including cancer, cardiovascular and
neurodegenerative diseases. Pharmaceutical interventions that slow down ageing and …
neurodegenerative diseases. Pharmaceutical interventions that slow down ageing and …
Insulin-Like Peptides Regulate Feeding Preference and Metabolism in Drosophila
UV Semaniuk, DV Gospodaryov, KM Feden'Ko… - Frontiers in …, 2018 - frontiersin.org
Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in
the regulation of carbohydrate concentrations in hemolymph as well as in accumulation of …
the regulation of carbohydrate concentrations in hemolymph as well as in accumulation of …
Metabolic Syndrome: Lessons from Rodent and Drosophila Models
Overweight and obesity are health conditions tightly related to a number of metabolic
complications collectively called “metabolic syndrome”(MetS). Clinical diagnosis of MetS …
complications collectively called “metabolic syndrome”(MetS). Clinical diagnosis of MetS …
[HTML][HTML] The Drosophila model to interrogate triacylglycerol biology
C Heier, S Klishch, O Stilbytska, U Semaniuk… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The deposition of storage fat in the form of triacylglycerol (TAG) is an evolutionarily
conserved strategy to cope with fluctuations in energy availability and metabolic stress …
conserved strategy to cope with fluctuations in energy availability and metabolic stress …