Environmental influences on the epigenome: exposure-associated DNA methylation in human populations

EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

The burden of pediatric asthma

G Ferrante, S La Grutta - Frontiers in pediatrics, 2018 - frontiersin.org
Asthma is the most common chronic disease in children, imposing a consistent burden on
health system. In recent years, prevalence of asthma symptoms became globally increased …

Air pollution and DNA methylation: effects of exposure in humans

CF Rider, C Carlsten - Clinical epigenetics, 2019 - Springer
Air pollution exposure is estimated to contribute to approximately seven million early deaths
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …

Epigenetics and allergy: from basic mechanisms to clinical applications

DP Potaczek, H Harb, S Michel, BA Alhamwe… - …, 2017 - Taylor & Francis
Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …

Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis

O Gruzieva, CJ Xu, P Yousefi, C Relton… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Prenatal exposure to air pollution has been associated with childhood
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …

Asthma-COPD overlap syndrome: pathogenesis, clinical features, and therapeutic targets

JM Leung, DD Sin - Bmj, 2017 - bmj.com
Asthma-COPD overlap syndrome (ACOS) or asthma-COPD overlap captures the subset of
patients with airways disease who have features of both asthma and chronic obstructive …

Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants

S Pauwels, M Ghosh, RC Duca, B Bekaert, K Freson… - Clinical …, 2017 - Springer
Background Maternal nutrition during pregnancy and infant nutrition in the early postnatal
period (lactation) are critically involved in the development and health of the newborn infant …

Particulate matter exposure shapes DNA methylation through the lifespan

L Ferrari, M Carugno, V Bollati - Clinical epigenetics, 2019 - Springer
Exposure to airborne particulate matter (PM) has been associated with detrimental health
effects. DNA methylation represents the most well-studied epigenetic factor among the …

Recent findings in the genetics and epigenetics of asthma and allergy

M Kabesch, J Tost - Seminars in immunopathology, 2020 - Springer
In asthma and allergy genetics, a trend towards a few main topics developed over the last 2
years. First, a number of studies have been published recently which focus on overlapping …

Multi-omics profiling approach to asthma: an evolving paradigm

Y Gautam, E Johansson, TB Mersha - Journal of personalized medicine, 2022 - mdpi.com
Asthma is a complex multifactorial and heterogeneous respiratory disease. Although
genetics is a strong risk factor of asthma, external and internal exposures and their …