An established mechanistic and clinical role for prophylaxis against paediatric respiratory
infections by nonspecific immunomodulators exists. Clinical trials underway promise to …

Objective This review focuses on the current understanding of the molecular mechanisms of
bacterial lysates, evidence of an induction of innate immunity, and the interaction with …

Context: Respiratory tract infections (RTIs) affect children all over the world and are
associated with significant morbidity and mortality. RTIs are usually triggered by viruses …

In light of an escalating prevalence of allergic disorders, it is crucial to fully comprehend their
pathophysiology and etiology. Such knowledge would play a pivotal role in the search for …

Wheezing and asthma are a growing cause of morbidity in children and adults. Treatment is
aimed at prevention of disease exacerbations and preservation of lung function. Respiratory …

The role of myeloid differentiation factor 88 (MyD88) in malignant tumors is largely unknown.
Therefore, in this study, we aimed to examine the function and underlying mechanism of …

In healthy infants and young children, the development of respiratory tract infections (RTIs) is
extremely common. In this paper, we present an international consensus of the available …

Secondary bacterial infections following influenza infection are a pressing problem facing
respiratory medicine. Although antibiotic treatment has been highly successful over recent …

Recurrent respiratory tract infections (rRTIs), of which there are three main groups—otitis
media, tonsillitis and sinusopathies—are very common in paediatric populations and are …

Recurrent respiratory tract infections (RRTIs) are the first leading cause of community‐and
nosocomial‐acquired infections. Antibiotics remain the mainstay of treatment, enhancing the …