[HTML][HTML] The role of polymorphism in various potential genes on polycystic ovary syndrome susceptibility and pathogenesis

H Chaudhary, J Patel, NK Jain, R Joshi - Journal of ovarian research, 2021 - Springer
Polycystic ovary syndrome (PCOS) is the most common endocrinopathies affecting the early
reproductive age in women, whose pathophysiology perplexes many researchers till today …

[HTML][HTML] Endocrine disrupting chemicals in polycystic ovary syndrome: the relevant role of the theca and granulosa cells in the pathogenesis of the ovarian dysfunction

M Jozkowiak, H Piotrowska-Kempisty, D Kobylarek… - Cells, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common heterogeneous endocrine disorder
among women of reproductive age. The pathogenesis of PCOS remains elusive; however …

Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype

JM McAllister, B Modi, BA Miller… - Proceedings of the …, 2014 - National Acad Sciences
Polycystic ovary syndrome (PCOS), characterized by increased ovarian androgen
biosynthesis, anovulation, and infertility, affects 5–7% of reproductive-age women. Genome …

[HTML][HTML] Luteinizing hormone and human chorionic gonadotropin: origins of difference

J Choi, J Smitz - Molecular and cellular endocrinology, 2014 - Elsevier
Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) are widely recognized
for their roles in ovulation and the support of early pregnancy. Aside from the timing of …

Genetics of the polycystic ovary syndrome

G Kosova, M Urbanek - Molecular and cellular endocrinology, 2013 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly complex endocrine disorder, characterized by
hyperandrogenemia, menstrual irregularities and polycystic ovaries. A strong genetic …

[HTML][HTML] Genetic determinants of polycystic ovary syndrome: progress and future directions

MR Jones, MO Goodarzi - Fertility and sterility, 2016 - Elsevier
The field of the genetics of polycystic ovary syndrome (PCOS) has relatively recently moved
into the era of genome-wide association studies. This has led to the discovery of 16 robust …

Genetics of polycystic ovary syndrome

K Mykhalchenko, D Lizneva, T Trofimova… - Expert review of …, 2017 - Taylor & Francis
Introduction: Polycystic ovary syndrome (PCOS) is a hormonal and metabolic disorder
affecting 5 to 20% of reproductive-aged women worldwide that results in androgen excess …

Cross-ethnic meta-analysis of genetic variants for polycystic ovary syndrome

YV Louwers, L Stolk, AG Uitterlinden… - The Journal of Clinical …, 2013 - academic.oup.com
Context: Genome-wide association studies (GWAS) have revealed new susceptibility loci for
Chinese patients with polycystic ovary syndrome (PCOS). Because ethnic background adds …

Evidence for chromosome 2p16. 3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry

P Mutharasan, E Galdones… - The Journal of …, 2013 - academic.oup.com
Context: A previous genome-wide association study in Chinese women with polycystic ovary
syndrome (PCOS) identified a region on chromosome 2p16. 3 encoding the LH …

Genotype–phenotype correlations of PCOS susceptibility SNPs identified by GWAS in a large cohort of Han Chinese women

L Cui, H Zhao, B Zhang, Z Qu, J Liu, X Liang… - Human …, 2013 - academic.oup.com
STUDY QUESTION Are there any correlations between the phenotypes of polycystic ovary
syndrome (PCOS) and the genotypes of the PCOS susceptibility single nucleotide …