Assembly, structure, function and regulation of type III secretion systems

W Deng, NC Marshall, JL Rowland… - Nature Reviews …, 2017 - nature.com
Type III secretion systems (T3SSs) are protein transport nanomachines that are found in
Gram-negative bacterial pathogens and symbionts. Resembling molecular syringes, T3SSs …

Structural insights into type III secretion systems of the bacterial flagellum and injectisome

LJ Worrall, DD Majewski… - Annual Review of …, 2023 - annualreviews.org
Two of the most fascinating bacterial nanomachines—the broadly disseminated rotary
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …

Analysis of the chronic wound microbiota of 2,963 patients by 16S rDNA pyrosequencing

RD Wolcott, JD Hanson, EJ Rees… - Wound repair and …, 2016 - Wiley Online Library
The extent to which microorganisms impair wound healing is an ongoing controversy in the
management of chronic wounds. Because the high diversity and extreme variability of the …

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

R Simeone, A Bobard, J Lippmann, W Bitter… - PLoS …, 2012 - journals.plos.org
Survival within macrophages is a central feature of Mycobacterium tuberculosis
pathogenesis. Despite significant advances in identifying new immunological parameters …

Behind the lines–actions of bacterial type III effector proteins in plant cells

D Büttner - FEMS microbiology reviews, 2016 - academic.oup.com
Pathogenicity of most Gram-negative plant-pathogenic bacteria depends on the type III
secretion (T3S) system, which translocates bacterial effector proteins into plant cells. Type III …

Protein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant-and animal-pathogenic bacteria

D Büttner - Microbiology and Molecular Biology Reviews, 2012 - Am Soc Microbiol
Flagellar and translocation-associated type III secretion (T3S) systems are present in most
Gram-negative plant-and animal-pathogenic bacteria and are often essential for bacterial …

Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors

R Figueira, DW Holden - Microbiology, 2012 - microbiologyresearch.org
Salmonella enterica serovars cause severe disease in humans, such as gastroenteritis and
typhoid fever. The bacteria are able to invade and replicate within host cells, including …

Type III secretion systems: the bacterial flagellum and the injectisome

A Diepold, JP Armitage - Philosophical Transactions of …, 2015 - royalsocietypublishing.org
The flagellum and the injectisome are two of the most complex and fascinating bacterial
nanomachines. At their core, they share a type III secretion system (T3SS), a transmembrane …

[HTML][HTML] The polymicrobial nature of biofilm infection

R Wolcott, JW Costerton, D Raoult, SJ Cutler - Clinical Microbiology and …, 2013 - Elsevier
The model of biofilm infection was first proposed over a decade ago. Recent scientific
advances have added much to our understanding of biofilms, usually polymicrobial …

Type three secretion system in attaching and effacing pathogens

MO Gaytán, VI Martínez-Santos, E Soto… - Frontiers in cellular …, 2016 - frontiersin.org
Enteropathogenic Escherichia coli and enterohemorrhagic E. coli are diarrheagenic
bacterial human pathogens that cause severe gastroenteritis. These enteric pathotypes …