Fluidised beds are commonly used in the pharmaceutical industry for granulation, drying
and coating of powder or pellets. The product quality strongly depends on the operation of …

The implementation of continuous pharmaceutical manufacturing requires advanced control
strategies rather than traditional end product testing or an operation within a small range of …

Pharmaceutical continuous manufacturing is considered as an emerging technology by the
regulatory agencies, which have defined a framework guided by an effective quality risk …

The release of the FDA's guidance on Process Analytical Technology has motivated and
supported the pharmaceutical industry to deliver consistent quality medicine by acquiring a …

In this research, the Consigma25 Continuous Manufacturing (CM) Line is statistically
analysed and modelled. First, the main effects plot is employed to examine the effects of …

This paper compares batch and continuous technologies in terms of product quality and
process performance in pharmaceutical tablet manufacturing using ethenzamide as the …

Process models are a growing tool for pharmaceutical manufacturing process design and
control. The Industry 4.0 paradigm promises to increase the amount of data available to …

The tablet manufacturing process is a complex system, especially in continuous
manufacturing (CM). It includes multiple unit operations, such as mixing, granulation, and …

Continuous manufacturing (CM) has the potential to provide pharmaceutical products with
better quality, improved yield and with reduced cost and time. Moreover, ease of scale-up …

Purpose The implementation of continuous processing technologies for pharmaceutical
manufacturing has increased due to its potential to enhance supply chain flexibility, reduce …