[HTML][HTML] Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment
NA Valdez-Cruz, E García-Hernández, C Espitia… - Microbial cell …, 2021 - Springer
SARS-CoV-2 is a novel β-coronavirus that caused the COVID-19 pandemic disease, which
spread rapidly, infecting more than 134 million people, and killing almost 2.9 million thus far …
spread rapidly, infecting more than 134 million people, and killing almost 2.9 million thus far …
[PDF][PDF] Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients
Y Li, M Ma, Q Lei, F Wang, W Hong, D Lai, H Hou, Z Xu… - Cell reports, 2021 - cell.com
To fully decipher the immunogenicity of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a …
(SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a …
Designed proteins assemble antibodies into modular nanocages
INTRODUCTION Antibodies that bind tightly to targets of interest play central roles in
biological research and medicine. Clusters of antibodies, typically generated by fusing …
biological research and medicine. Clusters of antibodies, typically generated by fusing …
[HTML][HTML] Potent molecular feature-based neutralizing monoclonal antibodies as promising therapeutics against SARS-CoV-2 infection
The 2019–2020 winter was marked by the emergence of a new coronavirus (SARS-CoV-2)
related disease (COVID-19), which started in Wuhan, China. Its high human-to-human …
related disease (COVID-19), which started in Wuhan, China. Its high human-to-human …
[HTML][HTML] Prediction and mitigation of mutation threats to COVID-19 vaccines and antibody therapies
Antibody therapeutics and vaccines are among our last resort to end the raging COVID-19
pandemic. They, however, are prone to over 5000 mutations on the spike (S) protein …
pandemic. They, however, are prone to over 5000 mutations on the spike (S) protein …
[HTML][HTML] Cross-reactive SARS-CoV-2 neutralizing antibodies from deep mining of early patient responses
Passive immunization using monoclonal antibodies will play a vital role in the fight against
COVID-19. The recent emergence of viral variants with reduced sensitivity to some current …
COVID-19. The recent emergence of viral variants with reduced sensitivity to some current …
[HTML][HTML] Native, engineered and de novo designed ligands targeting the SARS-CoV-2 spike protein
CFS Costa, AJM Barbosa, AMGC Dias… - Biotechnology …, 2022 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
deadly coronavirus disease 2019 (Covid-19) and is a concerning hazard to public health …
deadly coronavirus disease 2019 (Covid-19) and is a concerning hazard to public health …
[HTML][HTML] An antigenic space framework for understanding antibody escape of SARS-CoV-2 variants
The evolution of mutations in SARS-CoV-2 at antigenic sites that impact neutralizing
antibody responses in humans poses a risk to immunity developed through vaccination and …
antibody responses in humans poses a risk to immunity developed through vaccination and …
Applying Flow Virometry to Study the HIV Envelope Glycoprotein and Differences across HIV Model Systems
J Burnie, C Fernandes, A Patel, AT Persaud… - Viruses, 2024 - mdpi.com
The HIV envelope glycoprotein (Env) is a trimeric protein that facilitates viral binding and
fusion with target cells. As the sole viral protein on the HIV surface, Env is important both for …
fusion with target cells. As the sole viral protein on the HIV surface, Env is important both for …
Epitope profiling of coronavirus-binding antibodies using computational structural modelling
Identifying the epitope of an antibody is a key step in understanding its function and its
potential as a therapeutic. It is well-established in the literature that sequence-based clonal …
potential as a therapeutic. It is well-established in the literature that sequence-based clonal …