Metabolomics for investigating physiological and pathophysiological processes

DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

The mutual interplay of gut microbiota, diet and human disease

P Illiano, R Brambilla, C Parolini - The FEBS journal, 2020 - Wiley Online Library
The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …

[HTML][HTML] Whole fruits and fruit fiber emerging health effects

ML Dreher - Nutrients, 2018 - mdpi.com
Less than 10% of most Western populations consume adequate levels of whole fruits and
dietary fiber with typical intake being about half of the recommended levels. Evidence of the …

Gut microbiota: A player in aging and a target for anti-aging intervention

AM Vaiserman, AK Koliada, F Marotta - Ageing research reviews, 2017 - Elsevier
Aging-associated alterations in composition, diversity and functional features of intestinal
microbiota are well-described in the modern literature. They are suggested to be caused by …

Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease

H Chu, Y Duan, L Yang, B Schnabl - Gut, 2019 - gut.bmj.com
The spectrum of non-alcoholic fatty liver disease (NAFLD) ranges from simple hepatic
steatosis, commonly associated with obesity, to non-alcoholic steatohepatitis, which can …

Polysaccharide degradation by the intestinal microbiota and its influence on human health and disease

DW Cockburn, NM Koropatkin - Journal of molecular biology, 2016 - Elsevier
Carbohydrates comprise a large fraction of the typical diet, yet humans are only able to
directly process some types of starch and simple sugars. The remainder transits the large …

[HTML][HTML] Gut microbiota diversity according to dietary habits and geographical provenance

B Senghor, C Sokhna, R Ruimy, JC Lagier - Human Microbiome Journal, 2018 - Elsevier
The gut microbiota is an ecosystem including all bacterial species that permanently colonize
the gastro intestinal tract and a large number of other microorganisms from the environment …

Systematic review with meta‐analysis: breastfeeding and the risk of Crohn's disease and ulcerative colitis

L Xu, P Lochhead, Y Ko, B Claggett… - Alimentary …, 2017 - Wiley Online Library
Background Breastfeeding is a modifiable factor that may influence development of
inflammatory bowel diseases. However, literature on this has been inconsistent and not …

Gut microbiota, bacterial translocation, and interactions with diet: pathophysiological links between major depressive disorder and non-communicable medical …

A Slyepchenko, M Maes, FN Jacka, CA Köhler… - Psychotherapy and …, 2016 - karger.com
Background: Persistent low-grade immune-inflammatory processes, oxidative and
nitrosative stress (O&NS), and hypothalamic-pituitary-adrenal axis activation are integral to …

Role of oxidative stress and antioxidants in daily nutrition and human health

G Bjørklund, S Chirumbolo - Nutrition, 2017 - Elsevier
Diet is a complex process that we are just beginning to fully understand. We need to develop
a deeper comprehension of metabolism, energy balance, the molecular pathways involved …