Quantification of amyloid PET for future clinical use: a state-of-the-art review
Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer's
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …
Validation of amyloid PET positivity thresholds in centiloids: a multisite PET study approach
Background Inconsistent positivity thresholds, image analysis pipelines, and quantitative
outcomes are key challenges of multisite studies using more than one β-amyloid (Aβ) …
outcomes are key challenges of multisite studies using more than one β-amyloid (Aβ) …
Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer's disease
Abstract Background The Centiloid scale was developed to standardise the results of beta-
amyloid (Aβ) PET. We aimed to determine the Centiloid unit (CL) thresholds for CERAD …
amyloid (Aβ) PET. We aimed to determine the Centiloid unit (CL) thresholds for CERAD …
Relationship between amyloid and tau levels and its impact on tau spreading
Purpose Previous studies have shown that Aβ-amyloid (Aβ) likely promotes tau to spread
beyond the medial temporal lobe. However, the Aβ levels necessary for tau to spread in the …
beyond the medial temporal lobe. However, the Aβ levels necessary for tau to spread in the …
Amyloid PET quantification using low-dose CT-guided anatomic standardization
H Matsuda, T Yamao, M Shakado, Y Shigemoto… - EJNMMI research, 2021 - Springer
Background Centiloid (CL) scaling has become a standardized quantitative measure in
amyloid PET because it facilitates the direct comparison of results across institutions, even …
amyloid PET because it facilitates the direct comparison of results across institutions, even …
[PDF][PDF] Quantification of amyloid PET for future clinical use: a state‑of‑the‑art
Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer's
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …