Cellular models have created opportunities to explore the characteristics of human diseases
through well-established protocols, while avoiding the ethical restrictions associated with …

Over a decade ago, a landmark study that reported derivation of induced Pluripotent Stem
Cells (iPSCs) by reprogramming fibroblasts has transformed stem cell research attracting …

Skeletal muscle is the most abundant human tissue; therefore, an unlimited availability of
myogenic cells has applications in regenerative medicine and drug development. Here we …

Stem cells are capable of renewing themselves through cell division and have the
remarkable ability to differentiate into many different types of cells. They therefore have the …

More than a decade ago, a pioneering study reported generation of induced Pluripotent
Stem Cells (iPSCs) by ectopic expression of a cocktail of reprogramming factors in …

Tooth derived stem cells or dental stem cells are categorized according to the location from
which they are isolated and represent a promising source of cells for regenerative medicine …

Regenerative medicine promises to greatly impact on human health by improving repair
outcomes in a range of tissues and injury contexts. Successful therapies will rely on …

Neurodevelopmental disorders such as those linked to intellectual disabilities or autism
spectrum disorder are thought to originate in part from genetic defects in synaptic proteins …

Background Fabry disease (FD) is a lysosomal storage disease in which glycosphingolipids
(GB3) accumulate in organs of the human body, leading to idiopathic hypertrophic …

Diabetes mellitus (DM) is a group of metabolic disorders characterized by high blood
glucose levels due to insufficient insulin secretion, insulin action, or both. The present-day …