microRNA dysregulation in neurodegenerative diseases: A systematic review

CA Juźwik, SS Drake, Y Zhang, N Paradis-Isler… - Progress in …, 2019 - Elsevier
While the root causes for individual neurodegenerative diseases are distinct, many shared
pathological features and mechanisms contribute to neurodegeneration across diseases …

Brain-immune interactions in perinatal hypoxic-ischemic brain injury

B Li, K Concepcion, X Meng, L Zhang - Progress in neurobiology, 2017 - Elsevier
Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

[HTML][HTML] miR-223: an effective regulator of immune cell differentiation and inflammation

P Jiao, XP Wang, ZM Luoreng, J Yang… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) play a critical role in regulating various biological processes, such as
cell differentiation and immune modulation by binding to their target genes. miR-223 is a …

MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy

B Li, C Dasgupta, L Huang, X Meng… - Cellular & Molecular …, 2020 - nature.com
Neuroinflammation is a major contributor to secondary neuronal injury that accounts for a
significant proportion of final brain cell loss in neonatal hypoxic-ischemic encephalopathy …

miR-223: an immune regulator in infectious disorders

S Yuan, Q Wu, Z Wang, Y Che, S Zheng… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are diminutive noncoding RNAs that can influence disease
development and progression by post-transcriptionally regulating gene expression. The anti …

[HTML][HTML] Small non-coding RNAs as important players, biomarkers and therapeutic targets in multiple sclerosis: A comprehensive overview

E Piket, GY Zheleznyakova, L Kular, M Jagodic - Journal of autoimmunity, 2019 - Elsevier
Multiple sclerosis (MS) is a leading cause of progressive disability among young adults
caused by inflammation, demyelination and axonal loss in the central nervous system. Small …

MicroRNA-223 protects neurons from degeneration in experimental autoimmune encephalomyelitis

B Morquette, CA Juźwik, SS Drake, M Charabati… - Brain, 2019 - academic.oup.com
Multiple sclerosis is a chronic inflammatory, demyelinating, and neurodegenerative disease
affecting the brain, spinal cord and optic nerves. Neuronal damage is triggered by various …

Dysregulated microRNA involvement in multiple sclerosis by induction of T helper 17 cell differentiation

C Chen, Y Zhou, J Wang, Y Yan, L Peng… - Frontiers in …, 2018 - frontiersin.org
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous
system. Growing evidence has proven that T helper 17 (Th17) cells are one of the regulators …

Micro RNA‐mediated regulation of T helper type 17/regulatory T‐cell balance in autoimmune disease

C Liu, H Yang, W Shi, T Wang, Q Ruan - Immunology, 2018 - Wiley Online Library
Summary T helper type 17 (Th17) cells and regulatory T (Treg) cells are two distinct T‐cell
subsets with opposite effects on immune functions. While Th17 cells are a key effector in the …

Environmental influencers, microRNA, and multiple sclerosis

EMA Mohammed - Journal of central nervous system …, 2020 - journals.sagepub.com
Multiple sclerosis (MS) is a complex neurological disorder characterized by an aberrant
immune system that affects patients' quality of life. Several environmental factors have …