Histone-like proteins in bacteria contribute to the control of gene expression, as well as
participating in other DNA transactions such as recombination and DNA replication. They …

Escherichia coli is the best-known model for the biotechnological production of many
biotechnological products, including housekeeping and heterologous primary and …

According to recent experimental evidence, promoter architecture, defined by the number,
strength and regulatory role of the operators that control transcription, plays a major role in …

It is tempting to believe that we now own the genome. The ability to read and rewrite it at will
has ushered in a stunning period in the history of science. Nonetheless, there is an Achilles' …

Sustainable production of chemicals, materials, and pharmaceuticals is increasingly
performed by genetically engineered cell factories. Engineering of complex metabolic routes …

Escherichia coli HU protein is a dimer encoded by two closely related genes whose
expression is growth phase‐dependent. As a major component of the bacterial nucleoid, HU …

The Notch receptor contains a conserved ankyrin repeat domain that is required for Notch‐
mediated signal transduction. The ankyrin domain of Drosophila Notch contains six ankyrin …

Replication of Vibrio cholerae chromosome 2 (Chr2) initiates when the Chr1 locus, crtS (C
hr2 r eplication t riggering s ite) duplicates. The site binds the Chr2 initiator, RctB, and the …

The study of transcription remains one of the centerpieces of modern biology with
implications in settings from development to metabolism to evolution to disease. Precision …

The effect of superhelicity of DNA templates on transcription is well documented in several
cases. However, the amount of supercoiling that is needed to bring about any changes and …