Cancer cachexia: molecular mechanisms and treatment strategies
T Setiawan, IN Sari, YT Wijaya, NM Julianto… - Journal of Hematology & …, 2023 - Springer
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
Muscle wasting in disease: molecular mechanisms and promising therapies
S Cohen, JA Nathan, AL Goldberg - Nature reviews Drug discovery, 2015 - nature.com
Atrophy occurs in specific muscles with inactivity (for example, during plaster cast
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …
The role of exercise in the interplay between myokines, hepatokines, osteokines, adipokines, and modulation of inflammation for energy substrate redistribution and …
AM Gonzalez-Gil, L Elizondo-Montemayor - Nutrients, 2020 - mdpi.com
Exercise is an effective strategy for preventing and treating obesity and its related
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …
Skeletal muscle fibrosis: an overview
MAA Mahdy - Cell and tissue research, 2019 - Springer
Extracellular matrix (ECM) is an essential component of skeletal muscle. It provides a
framework structure that holds myofibers and blood capillaries and nerves supplying the …
framework structure that holds myofibers and blood capillaries and nerves supplying the …
Myogenic regulatory factors: The orchestrators of myogenesis after 30 years of discovery
Prenatal and postnatal myogenesis share many cellular and molecular aspects. Myogenic
regulatory factors are basic Helix-Loop-Helix transcription factors that indispensably …
regulatory factors are basic Helix-Loop-Helix transcription factors that indispensably …
Myostatin as a biomarker of muscle wasting and other pathologies-state of the art and knowledge gaps
J Baczek, M Silkiewicz, ZB Wojszel - Nutrients, 2020 - mdpi.com
Sarcopenia is a geriatric syndrome with a significant impact on older patients' quality of life,
morbidity and mortality. Despite the new available criteria, its early diagnosis remains …
morbidity and mortality. Despite the new available criteria, its early diagnosis remains …
TGF-β family signaling in mesenchymal differentiation
I Grafe, S Alexander, JR Peterson… - Cold Spring …, 2018 - cshperspectives.cshlp.org
Mesenchymal stem cells (MSCs) can differentiate into several lineages during development
and also contribute to tissue homeostasis and regeneration, although the requirements for …
and also contribute to tissue homeostasis and regeneration, although the requirements for …
Myokines and resistance training: a narrative review
BEM Zunner, NB Wachsmuth, ML Eckstein… - International journal of …, 2022 - mdpi.com
In the last few years, the muscular system has gained attention due to the discovery of the
muscle-secretome and its high potency for retaining or regaining health. These cytokines …
muscle-secretome and its high potency for retaining or regaining health. These cytokines …
Uraemic sarcopenia: aetiology and implications
IH Fahal - Nephrology Dialysis Transplantation, 2014 - academic.oup.com
The term uraemic myopathy has been used loosely to describe the skeletal muscle
abnormalities in uraemic patients. However, it does not fully explain the observed …
abnormalities in uraemic patients. However, it does not fully explain the observed …
Biomarkers in sarcopenia: a multifactorial approach
F Curcio, G Ferro, C Basile, I Liguori, P Parrella… - Experimental …, 2016 - Elsevier
The slow and continuous loss of muscle mass that progresses with aging is defined as
“sarcopenia”. Sarcopenia represents an important public health problem, being closely …
“sarcopenia”. Sarcopenia represents an important public health problem, being closely …