Oxidants, antioxidants, and the degenerative diseases of aging.

BN Ames, MK Shigenaga… - Proceedings of the …, 1993 - National Acad Sciences
Metabolism, like other aspects of life, involves tradeoffs. Oxidant by-products of normal
metabolism cause extensive damage to DNA, protein, and lipid. We argue that this damage …

Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology

JM Cicchese, S Evans, C Hult, LR Joslyn… - Immunological …, 2018 - Wiley Online Library
Immune responses to pathogens are complex and not well understood in many diseases,
and this is especially true for infections by persistent pathogens. One mechanism that allows …

Helicobacter pylori Infection

S Suerbaum, P Michetti - New England Journal of Medicine, 2002 - Mass Medical Soc
H. pylori is one of the most common bacterial infections in human beings, and its discovery
20 years ago altered the diagnosis and treatment of gastroduodenal disease. This review …

[HTML][HTML] Review of current diagnostic methods and advances in Helicobacter pylori diagnostics in the era of next generation sequencing

D Pohl, PM Keller, V Bordier… - World journal of …, 2019 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is highly prevalent in the human population and may
lead to severe gastrointestinal pathology including gastric and duodenal ulcers, mucosa …

[HTML][HTML] Epidemiology of gastric cancer

KD Crew, AI Neugut - World journal of gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
The incidence and mortality of gastric cancer have fallen dramatically in US and elsewhere
over the past several decades. Nonetheless, gastric cancer remains a major public health …

Helicobacter pylori in health and disease

TL Cover, MJ Blaser - Gastroenterology, 2009 - Elsevier
Helicobacter pylori is highly adapted for colonization of the human stomach and is present in
about half of the human population. When present, H pylori is usually the numerically …

Infection with Helicobacter pylori Strains Possessing cagA Is Associated with an Increased Risk of Developing Adenocarcinoma of the Stomach

MJ Blaser, GI Perez-Perez, H Kleanthous, TL Cover… - Cancer research, 1995 - AACR
To determine whether infection with a Helicobacter pylori strain possessing cagA is
associated with an increased risk of development of adenocarcinoma of the stomach, we …

Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.

A Covacci, S Censini, M Bugnoli… - Proceedings of the …, 1993 - National Acad Sciences
Helicobacter pylori has been associated with gastritis, peptic ulcer, and gastric
adenocarcinoma. We report the nucleotide sequence and expression of an …

Emerging infections: microbial threats to health in the United States

SC Oaks Jr, RE Shope, J Lederberg - 1992 - books.google.com
The emergence of HIV disease and AIDS, the reemergence of tuberculosis, and the
increased opportunity for disease spread through international travel demonstrate the critical …

[HTML][HTML] Infection with Helicobacter pylori

IARC Working Group on the Evaluation of … - … , liver flukes and …, 1994 - ncbi.nlm.nih.gov
The presence of spiral-shaped bacteria on human gastric mucosa was first recognized
nearly one hundred years ago (Pel, 1899). These bacteria were isolated for the first time in …