BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …

The kynurenine pathway (KP) plays a critical role in generating cellular energy in the form of
nicotinamide adenine dinucleotide (NAD+). Because energy requirements are substantially …

Objective Tryptophan can be catabolised to various metabolites through host kynurenine
and microbial indole pathways. We aimed to examine relationships of host and microbial …

We present a multivariate metabotyping approach to assess the functional recovery of
nonhospitalized COVID-19 patients and the possible biochemical sequelae of “Post-Acute …

The tryptophan–kynurenine pathway (Trp–KYN) is the major route for tryptophan conversion
in the brain and in the periphery. Kynurenines display a wide range of biological actions …

OBJECTIVE Recent studies have highlighted the significance of the microbiome in human
health and disease. Changes in the metabolites produced by microbiota have been …

Background Studies with methodological advancements are warranted to confirm the
relation of red meat consumption to the incidence of type 2 diabetes (T2D). Objective We …

Although previous studies suggest that amino acids (AAs) and microbiota-related
metabolites (MRMs) are associated with type 2 diabetes mellitus (T2DM), the results remain …

Background Dietary diversity is essential for human health. The gut ecosystem provides a
potential link between dietary diversity, host metabolism, and health, yet this mechanism is …

The approach to studying diet–health relationships has progressively shifted from individual
dietary components to overall dietary patterns that affect the interaction and balance of low …