Flow cytometry (FCM) is a sophisticated technique that works on the principle of light
scattering and fluorescence emission by the specific fluorescent probe-labeled cells as they …

The ability to obtain a molecular-level understanding of the chemistry that takes place at
liquid/solid interfaces is key to the development and improvement of many chemical and …

While many diseases of aging have been linked to the immunological system, immune
metrics capable of identifying the most at-risk individuals are lacking. From the blood …

Cell-to-cell variability of gene expression in clonal populations of mammalian cells is
ubiquitous. However, because molecular biologists habitually assume uniformity of the cell …

Flow cytometry allows high-content, multiparameter analysis of single cells, making it a
promising tool for drug discovery and profiling of intracellular signaling. To add high …

Background Recent advances in intracellular staining techniques, cytometer technology,
fluorescent reagents, and antibody production have expanded the number of intracellular …

Altered growth factor responses in phospho-protein-driven signaling networks are crucial to
cancer cell survival and pathology. Profiles of cancer cell signaling networks might therefore …

Phosphorylation is a common process for regulating protein functions. Studies have
confirmed that many human diseases are associated with the abnormal phosphorylation of …

Ofrece una introducción a las técnicas y experimentos científicos del pasado y del presente,
de descubrimientos importantes que llevaron a la formación de los conceptos clave en el …

Severe asthma is associated with the production of interleukin 17A (IL-17A). The exact role
of IL-17A in severe asthma and the factors that drive its production are unknown. Here we …