The lung microbiome is associated with host immune response and health outcomes in
experimental models and patient cohorts. Lung microbiome research is increasing in …

Abstract Germ-free (GF) mice, which are depleted of their resident microbiota, are the gold
standard for exploring the role of the microbiome in health and disease; however, they are of …

Chronic Human Immunodeficiency Virus (HIV) infection remains a significant challenge to
global public health. Despite advances in antiretroviral therapy (ART), which has …

The influence of gut microbiota on host immunity is widely studied, and its disturbance has
been linked to several immune-mediated disorders. Conversely, whether and how …

With the discovery of antiretroviral therapy, HIV-1 infection has transitioned into a
manageable but chronic illness, which requires lifelong treatment. Nevertheless, complete …

Complex organisms are associations of different cells that coexist and collaborate creating a
living consortium, the holobiont. The relationships between the holobiont members are …

Although antiretroviral therapy has transformed human immunodeficiency virus-type 1 (HIV-
1) from a deadly infection into a chronic disease, it does not clear the viral reservoir, leaving …

Humanized mouse models, created via transplantation of human hematopoietic tissues into
immune-deficient mice, support a number of research applications, including transplantation …

Harnessing the immune system to kill tumors has been revolutionary and, as a result, has
had an enormous benefit for patients in extending life and resulting in effective cures in …

High-fat diet (HFD) is well known to impact various aspects of gut health and has been
associated with many diseases and inflammation. However, the impact of HFD feeding on …