Alterations in brain intrinsic activity—as organized in resting-state networks (RSNs) such as
sensorimotor network (SMN), salience network (SN), and default-mode network (DMN) …

Neuroscientists have long observed that brain activity is naturally variable from moment-to-
moment, but neuroimaging research has largely ignored the potential importance of this …

Affective empathy (AE) is distinguished clinically and neurally from cognitive empathy (CE).
While AE is selectively disrupted in psychopathy, autism is associated with deficits in CE …

Importance The default mode network (DMN) is a collection of brain regions that reliably
deactivate during goal-directed behaviors and is more active during a baseline, or so-called …

BACKGROUND: Recent resting-state fMRI studies on major depressive disorder (MDD)
have found altered temporal correlation between low-frequency oscillations (LFOs) …

The inverse relation between serotonin and human aggression is often portrayed as
“reliable,”“strong,” and “well established” despite decades of conflicting reports and widely …

Previous research suggests overlap between brain regions that show task-induced
deactivations and those activated during the performance of social-cognitive tasks. Here, we …

Importance Although symptoms of irritability or anger are not central to the diagnosis of
unipolar major depressive episodes (MDEs), these symptoms have been found, in cross …

There is limited understanding of how monoamine-producing nuclei within midbrain and
brainstem contribute to the formation and functional dynamics of brain networks across the …

BACKGROUND: Reduced levels of serotonin (5-HT) within prefrontal cortex (PFC)–
amygdala circuits have long been implicated in impulsive aggression. However, whether …