Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Ginsenosides: a potential natural medicine to protect the lungs from lung cancer and inflammatory lung disease

L Wang, Y Zhang, Z Song, Q Liu, D Fan, X Song - Food & Function, 2023 - pubs.rsc.org
Lung cancer is the malignancy with the highest morbidity and mortality. Additionally,
pulmonary inflammatory diseases, such as pneumonia, acute lung injury, chronic obstructive …

Natural pachypodol integrated, lung targeted and inhaled lipid nanomedicine ameliorates acute lung injury via anti-inflammation and repairing lung barrier

ZC Sun, R Liao, C Xian, R Lin, L Wang, Y Fang… - Journal of Controlled …, 2024 - Elsevier
Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) is a high-mortality
disease caused by multiple disorders such as COVID-19, influenza, and sepsis. Current …

Heme oxygenase-1 ameliorates endotoxin-induced acute lung injury by modulating macrophage polarization via inhibiting TXNIP/NLRP3 inflammasome activation

X Wu, L Wu, Y Wu, W Chen, J Chen, L Gong… - Free Radical Biology and …, 2023 - Elsevier
Acute lung injury (ALI) remains a global public health issue without specific and effective
treatment options available in the clinic. Alveolar macrophage polarization is involved in the …

[HTML][HTML] Lung microbiome and origins of the respiratory diseases

J Belizário, M Garay-Malpartida, J Faintuch - Current Research in …, 2023 - Elsevier
The studies on the composition of the human microbiomes in healthy individuals, its
variability in the course of inflammation, infection, antibiotic therapy, diets and different …

Ursodeoxycholic acid alleviates sepsis-induced lung injury by blocking PANoptosis via STING pathway

Y He, J Deng, C Zhou, S Jiang, F Zhang, X Tao… - International …, 2023 - Elsevier
Acute lung injury (ALI), a progressive lung disease mostly caused by sepsis, is characterized
by uncontrolled inflammatory responses, increased oxidative stress, pulmonary barrier …

Role of stem cell derivatives in inflammatory diseases

Y Yang, Y Peng, Y Li, T Shi, Y Luan, C Yin - Frontiers in Immunology, 2023 - frontiersin.org
Mesenchymal stem cells (MSCs) are pluripotent stem cells of mesodermal origin with the
ability of self-renewal and multidirectional differentiation, which have all the common …

[HTML][HTML] Inhalable and bioactive lipid-nanomedicine based on bergapten for targeted acute lung injury therapy via orchestrating macrophage polarization

R Liao, ZC Sun, L Wang, C Xian, R Lin, G Zhuo… - Bioactive Materials, 2025 - Elsevier
Acute lung injury (ALI) or its more severe form, acute respiratory distress syndrome, is a life-
threatening disease closely associated with an imbalance of M1/M2 macrophage …

[HTML][HTML] Exploring immune-related pathogenesis in lung injury: Providing new insights Into ALI/ARDS

J Zheng, Y Li, X Kong, J Guo - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) represent a
significant global burden of morbidity and mortality, with lung injury being the primary cause …

Advances in the Application and Mechanism of Bioactive Peptides in the Treatment of Inflammation

H Liu, L Zhang, J Yu, S Shao - Frontiers in Immunology, 2024 - frontiersin.org
Inflammation is a normal immune response in organisms, but it often triggers chronic
diseases such as colitis and arthritis. Currently, the most widely used anti-inflammatory …