Advanced techniques for detecting protein misfolding and aggregation in cellular environments
Protein misfolding and aggregation, a key contributor to the progression of numerous
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …
Small molecular fluorescent probes for Alzheimer's disease associated active species
F Tang, K Wang, X Liu, X Zhang, W Zhou… - … A European Journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the main
cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is …
cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is …
A comprehensive analysis of the intrinsic visible fluorescence emitted by peptide/protein amyloid-like assemblies
Amyloid aggregation is a widespread process that involves proteins and peptides with
different molecular complexity and amino acid composition. The structural motif (cross-β) …
different molecular complexity and amino acid composition. The structural motif (cross-β) …
Decomposition analysis on the excitation behaviors of thiazolothiazole (TTz)-based dyes via the time-dependent dielectric density functional theory approach
T Naito, Y Kita, T Shimazaki, M Tachikawa - RSC advances, 2022 - pubs.rsc.org
Thiazolothiazole (TTz)-based materials have been attracting much attention because of their
widespread applications. In this paper, we discuss the excited electronic behaviors of …
widespread applications. In this paper, we discuss the excited electronic behaviors of …
[HTML][HTML] A versatile luminescent probe for sensing and monitoring amyloid proteins
G Vázquez, A Espargaró, AB Caballero… - Dyes and …, 2024 - Elsevier
A modified lysine residue containing an environment-sensitive moiety was prepared through
a straightforward synthesis, and its fluorescent properties were examined. The new …
a straightforward synthesis, and its fluorescent properties were examined. The new …
Auto-fluorescência em processos de agregação de péptidos e proteínas: beta-amilóide na presença de iões e lisozima sob condições promotoras de agregação
BRM Coutinho - 2022 - estudogeral.uc.pt
O estudo do mecanismo de formação de agregados proteicos é atualmente alvo de
interesse devido à sua frequente relação com doenças neurológicas como o Alzheimer …
interesse devido à sua frequente relação com doenças neurológicas como o Alzheimer …
[引用][C] Determining intracellular protein physical microenvironment using fluorescence lifetime imaging microscopy
Y Xiao, B Shen, H Huang - Trends in Biochemical Sciences, 2024 - cell.com
Pathological protein aggregation is an important feature of neurodegenerative diseases.
Fluorescence lifetime image microscopy (FLIM) is a technique that measures the time the …
Fluorescence lifetime image microscopy (FLIM) is a technique that measures the time the …