Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …
characterized by two core behavioral symptoms, namely impairments in social …
The roles of histamine and its receptor ligands in central nervous system disorders: An update
W Hu, Z Chen - Pharmacology & therapeutics, 2017 - Elsevier
The neurotransmitter histamine receives less attention compared with other biogenic
amines, because of its moderate action in the central nervous system (CNS). However …
amines, because of its moderate action in the central nervous system (CNS). However …
Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy
TC Thannickal, J John, L Shan, DF Swaab… - Science translational …, 2018 - science.org
The changes in brain function that perpetuate opiate addiction are unclear. In our studies of
human narcolepsy, a disease caused by loss of immunohistochemically detected hypocretin …
human narcolepsy, a disease caused by loss of immunohistochemically detected hypocretin …
Greatly increased numbers of histamine cells in human narcolepsy with cataplexy
J John, TC Thannickal, R McGregor… - Annals of …, 2013 - Wiley Online Library
Objective To determine whether histamine cells are altered in human narcolepsy with
cataplexy and in animal models of this disease. Methods Immunohistochemistry for histidine …
cataplexy and in animal models of this disease. Methods Immunohistochemistry for histidine …
Effects of an H3R antagonist on the animal model of autism induced by prenatal exposure to valproic acid
D Baronio, K Castro, T Gonchoroski, GM de Melo… - PloS one, 2015 - journals.plos.org
Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders primarily
characterized by impaired social interaction and communication, and by restricted repetitive …
characterized by impaired social interaction and communication, and by restricted repetitive …
The human histaminergic system in neuropsychiatric disorders
L Shan, AM Bao, DF Swaab - Trends in neurosciences, 2015 - cell.com
Histaminergic neurons are exclusively located in the hypothalamic tuberomamillary nucleus,
from where they project to many brain areas. The histaminergic system is involved in basic …
from where they project to many brain areas. The histaminergic system is involved in basic …
Histamine N-Methyltransferase in the Brain
T Yoshikawa, T Nakamura, K Yanai - International journal of molecular …, 2019 - mdpi.com
Brain histamine is a neurotransmitter and regulates diverse physiological functions.
Previous studies have shown the involvement of histamine depletion in several neurological …
Previous studies have shown the involvement of histamine depletion in several neurological …
[HTML][HTML] Histamine and the striatum
JP Bolam, TJ Ellender - Neuropharmacology, 2016 - Elsevier
The neuromodulator histamine is released throughout the brain during periods of
wakefulness. Combined with an abundant expression of histamine receptors, this suggests …
wakefulness. Combined with an abundant expression of histamine receptors, this suggests …
The other side of the histamine H3 receptor
BA Ellenbroek, B Ghiabi - Trends in neurosciences, 2014 - cell.com
Although histamine H3 receptors are predominantly known as presynaptic receptors,
regulating the release of neurotransmitters such as dopamine, acetylcholine, and histamine …
regulating the release of neurotransmitters such as dopamine, acetylcholine, and histamine …
Histamine: a new immunomodulatory player in the neuron-glia crosstalk
SM Rocha, J Pires, M Esteves, B Graça… - Frontiers in cellular …, 2014 - frontiersin.org
Histamine is an amine acting as a major peripheral inflammatory mediator. In the brain,
histamine was initially viewed as a neurotransmitter, but new evidences support its …
histamine was initially viewed as a neurotransmitter, but new evidences support its …