Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …

The neurotransmitter histamine receives less attention compared with other biogenic
amines, because of its moderate action in the central nervous system (CNS). However …

The changes in brain function that perpetuate opiate addiction are unclear. In our studies of
human narcolepsy, a disease caused by loss of immunohistochemically detected hypocretin …

Objective To determine whether histamine cells are altered in human narcolepsy with
cataplexy and in animal models of this disease. Methods Immunohistochemistry for histidine …

Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders primarily
characterized by impaired social interaction and communication, and by restricted repetitive …

Histaminergic neurons are exclusively located in the hypothalamic tuberomamillary nucleus,
from where they project to many brain areas. The histaminergic system is involved in basic …

Brain histamine is a neurotransmitter and regulates diverse physiological functions.
Previous studies have shown the involvement of histamine depletion in several neurological …

The neuromodulator histamine is released throughout the brain during periods of
wakefulness. Combined with an abundant expression of histamine receptors, this suggests …

Although histamine H3 receptors are predominantly known as presynaptic receptors,
regulating the release of neurotransmitters such as dopamine, acetylcholine, and histamine …

Histamine is an amine acting as a major peripheral inflammatory mediator. In the brain,
histamine was initially viewed as a neurotransmitter, but new evidences support its …