The aortic valve regulates unidirectional flow of oxygenated blood to the myocardium and
arterial system. The natural anatomical geometry and microstructural complexity ensures …

Cardiovascular disease (CVD) is one of the leading causes of death in the Western world.
The replacement of damaged vessels and valves has been practiced since the 1950's …

The tissue-engineered heart valve portends a new era in the field of valve replacement.
Decellularized heart valves are of great interest as a scaffold for the tissue-engineered heart …

Ischemic cardiomyopathy (ICM) affect millions of patients globally. Decellularized
extracellular matrix materials (dECM) have components, microstructure and mechanical …

Xenogeneic decellularized heart valve scaffolds have the potential to overcome the
limitations of existing bioprosthetic heart valves that have limited duration due to calcification …

The growing interest in the use of recyclable and biodegradable natural materials has
become a relevant topic in pharmaceutics. In this work, we suggest the use and valorization …

Decellularized biological scaffolds hold great promise in cardiovascular surgery. In order to
ensure off-the-shelf availability, routine use of decellularized scaffolds requires tissue …

Structural cardiac lesions are often surgically repaired using prosthetic patches, which can
be biological or synthetic. In the current clinical scenario, biological patches derived from the …

Nerve fibers of the peripheral nervous system (PNS) have a remarkable ability to regenerate
up to an almost complete recovery of normal function following a crush or a Sunderland …

Background Various detergent‐based protocols are used to remove cells and cellular debris
in porcine aortic valve (PAV). However, the removal of antigenic cellular components has …