[HTML][HTML] The role of radiolabeling in BNCT tracers for enhanced dosimetry and treatment planning
S Mushtaq, P Ji, JY Kim, KC Lee, KI Kim - Theranostics, 2023 - ncbi.nlm.nih.gov
Positron emission tomography (PET) and single photon emission computed tomography
(SPECT) are potent technologies for non-invasive imaging of pharmacological and …
(SPECT) are potent technologies for non-invasive imaging of pharmacological and …
Novel promising boron agents for boron neutron capture therapy: Current status and outlook on the future
H Xu, J Liu, R Li, J Lin, L Gui, Y Wang, Z Jin… - Coordination Chemistry …, 2024 - Elsevier
Abstract Boron Neutron Capture Therapy (BNCT) is an emerging binary radiation therapy
that exhibits high precision and lethlity for tumor. Its clinical efficacy has been demonstrated …
that exhibits high precision and lethlity for tumor. Its clinical efficacy has been demonstrated …
Development of probes for radiotheranostics with albumin binding moiety to increase the therapeutic effects of astatine-211 (211At)
H Echigo, K Mishiro, M Munekane, T Fuchigami… - European Journal of …, 2024 - Springer
Purpose We have developed probes for multiradionuclides radiotheranostics using RGD
peptide ([67Ga] Ga-DOTA-c [RGDf (4-I) K]([67Ga] 1) and Ga-DOTA-[211At] c [RGDf (4-At) …
peptide ([67Ga] Ga-DOTA-c [RGDf (4-I) K]([67Ga] 1) and Ga-DOTA-[211At] c [RGDf (4-At) …
Identification of a PH-Responsive Peptide–Paclitaxel Conjugate as a Novel Drug with Improved Therapeutic Potential
A highly sensitive, nontoxic, hydrophilic cell-penetrating peptide (CPP= c [RGDKLAK]) was
selected for the construction of an effective peptide–drug conjugate (PDC). A hydrophobic …
selected for the construction of an effective peptide–drug conjugate (PDC). A hydrophobic …
Development of a Gadolinium–Boron-Conjugated Albumin for MRI-Guided Neutron Capture Therapy
S Okada, K Nishimura, Q Ainaya… - Molecular …, 2023 - ACS Publications
Noninvasive monitoring of boron agent biodistribution is required in advance of neutron
capture therapy. In this study, we developed a gadolinium–boron-conjugated albumin (Gd …
capture therapy. In this study, we developed a gadolinium–boron-conjugated albumin (Gd …
Synthesis and Preclinical Evaluation of Urea-Based Prostate-Specific Membrane Antigen-Targeted Conjugates Labeled with 177Lu
AE Machulkin, SA Petrov, V Bodenko… - ACS pharmacology & …, 2024 - ACS Publications
177Lu-labeled small-molecule prostate-specific membrane antigen (PSMA) targeted tracers
are therapeutic agents for metastatic castration-resistant prostate cancer. Optimizing …
are therapeutic agents for metastatic castration-resistant prostate cancer. Optimizing …
[HTML][HTML] Boron-containing compounds as labels, drugs, and theranostic agents for diabetes and its complications
MA Soriano-Ursúa, RI Cordova-Chávez… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Diabetes is a disease with a high global burden. Current strategies have failed to limit the
advancement and impact of the disease. Successful early diagnosis and treatment will …
advancement and impact of the disease. Successful early diagnosis and treatment will …
Synthesis of closo-and nido-carborane derivatives of the KRGD peptide
DA Gruzdev, AV Vakhrushev, AM Demin… - Journal of …, 2024 - Elsevier
Peptides of the RGD family are of significant interest as vectors for targeted delivery of
various therapeutic and diagnostic groups to tumor cells. Their application can be especially …
various therapeutic and diagnostic groups to tumor cells. Their application can be especially …
[HTML][HTML] Peptide Conjugated Boron Neutron Capture Therapy for Enhanced Tumor Targeting
VGSS Jyothi, N Kommineni - Nanotheranostics, 2024 - ncbi.nlm.nih.gov
A cutting-edge non-invasive cancer treatment method called boron neutron capture therapy
(BNCT) allows for the removal of cancerous tumor cells with the least possible damage to …
(BNCT) allows for the removal of cancerous tumor cells with the least possible damage to …
Advances in tumor stroma-based targeted delivery
The tumor stroma plays a crucial role in tumor progression, and the interactions between the
extracellular matrix, tumor cells, and stromal cells collectively influence tumor progression …
extracellular matrix, tumor cells, and stromal cells collectively influence tumor progression …