Melatonin, more commonly known as the sleep hormone, is mainly secreted by the pineal
gland in dark conditions and regulates the circadian rhythm of the organism. Its intrinsic …

Exogenous melatonin has been investigated as treatment for a number of medical and
surgical diseases, demonstrating encouraging results. The aim of this review was to present …

Insomnia is a serious worldwide health threat, affecting nearly one third of the general
population. Melatonin has been reported to improve sleep efficiency and it was found that …

Cerebral palsy is caused by injury or developmental disturbances to the immature brain and
leads to substantial motor, cognitive, and learning deficits. In addition to developmental …

Lifestyle and genetic background are well known risk factors of cardiovascular disease
(CVD). A third contributing factor is suboptimal fetal development, due to nutrient or oxygen …

Newborns, and especially those delivered preterm, are probably more prone to oxidative
stress than individuals later in life. Also during pregnancy, increased oxygen demand …

Melatonin exhibits extraordinary diversity in terms of its functions and distribution. When
discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin …

The therapeutic potential of melatonin as a chronobiotic cytoprotective agent to counteract
the consequences of COVID-19 infections has been advocated. Because of its wide-ranging …

This review briefly summarizes the actions of melatonin in reducing molecular damage
caused by free radicals and associated oxygen-and nitrogenbased reactants. All the …

Maternal infection/inflammation represents one of the most important factors involved in the
etiology of brain injury in newborns. We investigated the modulating effect of prenatal …